UniProt P48240
Exosome complex component MTR3 (P48240)
Exosome complex component MTR3 (UniProt P48240): 15 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P48240
- Protein
- Exosome complex component MTR3
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
16 records of P48240 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4IFD | Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA | x-ray diffraction | F | — | — |
| 4IFD | Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA | x-ray diffraction | F | — | — |
| 4OO1 | Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA | x-ray diffraction | F | — | — |
| 4OO1 | Structure of an RRP6-RNA exosome complex bound to POLY(A) RNA | x-ray diffraction | F | — | — |
| 5C0W | Structure of a 12-subunit nuclear exosome complex bound to single- stranded RNA substrates | x-ray diffraction | F | — | — |
| 5C0X | Structure of a 12-subunit nuclear exosome complex bound to structured RNA | x-ray diffraction | F | — | — |
| 5G06 | Cryo-EM structure of yeast cytoplasmic exosome | electron microscopy | F | — | — |
| 5G06 | Cryo-EM structure of yeast cytoplasmic exosome | electron microscopy | F | — | — |
| 5JEA | Structure of a cytoplasmic 11-subunit RNA exosome complex including SKI7, bound to RNA | x-ray diffraction | F | — | — |
| 5K36 | Structure of an eleven component nuclear RNA exosome complex bound to RNA | x-ray diffraction | F | SO4 | — |
| 5K36 | Structure of an eleven component nuclear RNA exosome complex bound to RNA | x-ray diffraction | F | SO4 | — |
| 5OKZ | Crystal strucrure of the MPP6 exosome complex | x-ray diffraction | F, P, Z, j | — | — |
| 5VZJ | Structure of a twelve component MPP6-nuclear RNA exosome complex bound to RNA | x-ray diffraction | F | — | — |
| 6LQS | Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) | electron microscopy | M3 | — | — |
| 7AJT | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | electron microscopy | EG | — | 1 (best 0.86) |
| P48240 | AlphaFold monomer V2.0 prediction for exosome complex component MTR3 (P48240) | predicted | A | — | 2 (best 0.49) |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 5JEA chain F against the predicted model P48240: TM-score 0.99, RMSD 0.66 Å
- 4IFD chain F against the predicted model P48240: TM-score 0.98, RMSD 0.83 Å
- 4IFD chain F against the predicted model P48240: TM-score 0.98, RMSD 0.83 Å
- 5OKZ chain P against the predicted model P48240: TM-score 0.98, RMSD 0.87 Å
- 5OKZ chain F against the predicted model P48240: TM-score 0.98, RMSD 0.89 Å
- 4OO1 chain F against the predicted model P48240: TM-score 0.98, RMSD 0.90 Å
- 4OO1 chain F against the predicted model P48240: TM-score 0.98, RMSD 0.90 Å
- 5C0X chain F against the predicted model P48240: TM-score 0.97, RMSD 1.08 Å
- 5OKZ chain j against the predicted model P48240: TM-score 0.97, RMSD 0.97 Å
- 5OKZ chain Z against the predicted model P48240: TM-score 0.97, RMSD 0.98 Å
Elsewhere
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