AlphaFold monomer V2.0 prediction for exosome complex component MTR3 (P48240)

Structure

1 distinct chain · 32% helix, 28% strand (DSSP).

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 5C0X · Structure of a 12-subunit nuclear exosome complex bound to structured RNA · an experimental structure of the same protein · chain A against F, TM-score 0.84
• 4IFD · Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA · an experimental structure of the same protein · chain A against F, TM-score 0.84
• 4IFD · Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA · an experimental structure of the same protein · chain A against F, TM-score 0.84
• 5C0W · Structure of a 12-subunit nuclear exosome complex bound to single- stranded RNA substrates · an experimental structure of the same protein · chain A against F, TM-score 0.83
• 7AJT · Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) · an experimental structure of the same protein · chain A against EG, TM-score 0.83
• 7AJU · Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome) · an experimental structure of the same protein · chain A against EG, TM-score 0.83
• 7D4I · Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA… · an experimental structure of the same protein · chain A against M3, TM-score 0.83
• 6LQS · Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) · an experimental structure of the same protein · chain A against M3, TM-score 0.83
• 6FSZ · Structure of the nuclear RNA exosome · an experimental structure of the same protein · chain A against FF, TM-score 0.83
• 5JEA · Structure of a cytoplasmic 11-subunit RNA exosome complex including SKI7, bound to RNA · an experimental structure of the same protein · chain A against F, TM-score 0.83
• 5JEA · Structure of a cytoplasmic 11-subunit RNA exosome complex including Ski7, bound to RNA · an experimental structure of the same protein · chain A against F, TM-score 0.83
• 5K36 · Structure of an eleven component nuclear RNA exosome complex bound to RNA · an experimental structure of the same protein · chain A against F, TM-score 0.82

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P48240
• Elsewhere: UniProt P48240 · AlphaFold DB P48240