UniProt P46976
Glycogenin-1 (P46976)
Glycogenin-1 (UniProt P46976), EC 2.4.1.186: 39 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P46976
- Protein
- Glycogenin-1
- EC
- 2.4.1.186
- Experimental structures
- 39
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 10 · 1 record with a druggable one
Structures
40 records of P46976 in the MolNFT archive: 39 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3Q4S | Crystal Structure of Human Glycogenin-1 (GYG1), apo form | x-ray diffraction | A | — | — |
| 3Q4S | Crystal structure of human glycogenin-1 (GYG1), apo form | x-ray diffraction | A | — | — |
| 3QVB | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP | x-ray diffraction | A | — | — |
| 3QVB | Crystal structure of human glycogenin-1 (GYG1) complexed with manganese and udp | x-ray diffraction | A | — | — |
| 3RMV | Crystal Structure of Human Glycogenin-1 (GYG1) T83M mutant complexed with manganese and UDP | x-ray diffraction | A | — | — |
| 3RMV | Crystal structure of human glycogenin-1 (GYG1) T83M mutant complexed with manganese and udp | x-ray diffraction | A | — | — |
| 3RMW | Crystal Structure of Human Glycogenin-1 (GYG1) T83M mutant complexed with manganese and UDP-glucose | x-ray diffraction | A | — | — |
| 3RMW | Crystal structure of human glycogenin-1 (GYG1) T83M mutant complexed with manganese and udp-glucose | x-ray diffraction | A | — | — |
| 3T7M | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a triclinic… | x-ray diffraction | A, B | — | — |
| 3T7M | Crystal structure of human glycogenin-1 (GYG1) complexed with manganese and udp, in a triclinic… | x-ray diffraction | A, B | — | — |
| 3T7N | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a monoclinic… | x-ray diffraction | A, B | — | — |
| 3T7N | Crystal structure of human glycogenin-1 (GYG1) complexed with manganese and udp, in a monoclinic… | x-ray diffraction | A, B | — | — |
| 3T7O | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP-Glucose and glucose | x-ray diffraction | A, B | — | — |
| 3T7O | Crystal structure of human glycogenin-1 (GYG1) complexed with manganese, udp-glucose and glucose | x-ray diffraction | A, B | — | — |
| 3U2T | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese | x-ray diffraction | A | — | — |
| 3U2T | Crystal structure of human glycogenin-1 (GYG1) complexed with manganese | x-ray diffraction | A | — | — |
| 3U2U | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltotetraose | x-ray diffraction | A, B | — | — |
| 3U2U | Crystal structure of human glycogenin-1 (GYG1) complexed with manganese, udp and maltotetraose | x-ray diffraction | A, B | — | — |
| 3U2V | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and maltohexaose | x-ray diffraction | A, B | — | — |
| 3U2V | Crystal structure of human glycogenin-1 (GYG1) complexed with manganese, udp and maltohexaose | x-ray diffraction | A, B | — | — |
| 3U2W | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and glucose or a glucal… | x-ray diffraction | A, B | — | — |
| 3U2W | Crystal structure of human glycogenin-1 (GYG1) complexed with manganese and glucose or a glucal… | x-ray diffraction | A, B | — | — |
| 3U2X | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and 1'-deoxyglucose | x-ray diffraction | A, B | — | — |
| 3U2X | Crystal structure of human glycogenin-1 (GYG1) complexed with manganese, udp and 1'-deoxyglucose | x-ray diffraction | A, B | — | — |
| 6EQJ | Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant, apo form | x-ray diffraction | A | — | — |
| 6EQJ | Crystal structure of human glycogenin-1 (GYG1) TYR195PIPHE mutant, apo form | x-ray diffraction | A | — | — |
| 6EQL | Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant complexed with manganese and UDP | x-ray diffraction | A, B | UDP, MN | — |
| 6EQL | Crystal structure of human glycogenin-1 (GYG1) TYR195PIPHE mutant complexed with manganese and udp | x-ray diffraction | A, B | UDP, MN | — |
| 7Q0B | Human GYS1-GYG1 complex inhibited state | electron microscopy | E, F, G, H | — | — |
| 7Q0S | Human GYS1-GYG1 complex inhibited-like state bound to glucose-6-phosphate | electron microscopy | E, F, G, H | — | — |
| 7Q0S | Human GYS1-GYG1 complex inhibited-like state bound to glucose-6- phosphate | electron microscopy | E, F, G, H | — | — |
| 7Q12 | Human GYS1-GYG1 complex activated state bound to glucose-6-phosphate | electron microscopy | E, F, G, H | — | — |
| 7Q13 | Human GYS1-GYG1 complex activated state bound to glucose-6-phosphate, uridine diphosphate, and… | electron microscopy | E, F, G, H | — | — |
| 7ZBN | Cryo-EM structure of the human gs-gn complex in the inhibited state | electron microscopy | E, F, G, H | — | — |
| 8CVX | Human glycogenin-1 and glycogen synthase-1 complex in the presence of glucose-6-phosphate | electron microscopy | E, H, G, F | — | — |
| 8CVX | Human glycogenin-1 and glycogen synthase-1 complex in the presence of glucose-6-phosphate | electron microscopy | E, H, G, F | — | — |
| 8CVY | Human glycogenin-1 and glycogen synthase-1 complex in the apo mobile state | electron microscopy | E, G, H | — | — |
| 8CVZ | Human glycogenin-1 and glycogen synthase-1 complex in the apo ordered state | electron microscopy | J, E, I, F, G, H | — | 10 (best 0.79) |
| 8CVZ | Human glycogenin-1 and glycogen synthase-1 complex in the apo ordered state | electron microscopy | J, E, I, F, G, H | — | — |
| P46976 | AlphaFold monomer V2.0 prediction for glycogenin-1 (P46976) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3T7N chain A against the predicted model P46976: TM-score 0.99, RMSD 0.53 Å
- 3T7N chain A against the predicted model P46976: TM-score 0.99, RMSD 0.53 Å
- 3U2U chain A against the predicted model P46976: TM-score 0.99, RMSD 0.55 Å
- 3U2U chain A against the predicted model P46976: TM-score 0.99, RMSD 0.55 Å
- 3U2X chain A against the predicted model P46976: TM-score 0.99, RMSD 0.61 Å
- 3U2X chain A against the predicted model P46976: TM-score 0.99, RMSD 0.61 Å
- 3U2V chain A against the predicted model P46976: TM-score 0.99, RMSD 0.63 Å
- 3U2V chain A against the predicted model P46976: TM-score 0.99, RMSD 0.63 Å
- 3T7M chain A against the predicted model P46976: TM-score 0.99, RMSD 0.63 Å
- 3T7M chain A against the predicted model P46976: TM-score 0.99, RMSD 0.63 Å
Elsewhere
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