UniProt P46151
Methylenetetrahydrofolate reductase 1 (P46151)
Methylenetetrahydrofolate reductase 1 (UniProt P46151), EC 1.5.1.20: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P46151
- Protein
- Methylenetetrahydrofolate reductase 1
- EC
- 1.5.1.20
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 2 records with a druggable one
Structures
3 records of P46151 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6FNU | Structure of S. cerevisiae Methylenetetrahydrofolate reductase 1, catalytic domain | x-ray diffraction | A | FAD | 3 (best 0.69) |
| 6FNU | Structure of S. cerevisiae methylenetetrahydrofolate reductase 1, catalytic domain | x-ray diffraction | A | FAD | — |
| P46151 | AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate reductase 1 (P46151) | predicted | A | — | 5 (best 0.85) |
Ligands
- FAD · Flavin-adenine dinucleotide · in 2 records
Experiment against prediction
- 6FNU chain A against the predicted model P46151: TM-score 0.95, RMSD 1.17 Å
- 6FNU chain A against the predicted model P46151: TM-score 0.95, RMSD 1.17 Å
Elsewhere
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