UniProt P45974
Ubiquitin carboxyl-terminal hydrolase 5 (P45974)
Ubiquitin carboxyl-terminal hydrolase 5 (UniProt P45974), EC 3.4.19.12: 20 experimental structures on GenesisL1, 11 ligands bound, 2 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P45974
- Protein
- Ubiquitin carboxyl-terminal hydrolase 5
- EC
- 3.4.19.12
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 11
- Pockets
- 2 · 0 records with a druggable one
Structures
20 records of P45974 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DAG | Solution Structure of the First UBA Domain in the Human Ubiquitin Specific Protease 5 (Isopeptidase… | solution nmr | A | — | — |
| 2DAG | Solution structure of the first uba domain in the human ubiquitin specific protease 5 (isopeptidase… | solution nmr | A | — | — |
| 2DAK | Solution Structure of the Second UBA Domain in the Human Ubiquitin Specific Protease 5… | solution nmr | A | — | — |
| 2DAK | Solution structure of the second uba domain in the human ubiquitin specific protease 5… | solution nmr | A | — | — |
| 2G43 | Structure of the ZNF UBP domain from deubiquitinating enzyme isopeptidase T (IsoT) | x-ray diffraction | A, B | — | — |
| 2G43 | Structure of the znf ubp domain from deubiquitinating enzyme isopeptidase T (isot) | x-ray diffraction | A, B | — | — |
| 2G45 | Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase T (isot) in… | x-ray diffraction | A, D | — | — |
| 2G45 | Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase T (isot) in… | x-ray diffraction | A, D | — | — |
| 3IHP | Covalent ubiquitin-USP5 complex | x-ray diffraction | — | — | |
| 6DXH | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with… | x-ray diffraction | A | UNX, ZN, HH4 | — |
| 6DXT | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with… | x-ray diffraction | A, B | HHY, UNX, ZN | — |
| 6NFT | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with… | x-ray diffraction | A, B | ZN, KKG, UNX | — |
| 6P9G | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with… | x-ray diffraction | A | ZN, O4Y, UNX | — |
| 6P9G | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with… | x-ray diffraction | A | ZN, O4Y, UNX | — |
| 7MS5 | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with… | x-ray diffraction | A, B | ZN, ZOG, CA | 2 (best 0.41) |
| 7MS5 | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with… | x-ray diffraction | A, B | ZN, ZOG, CA | — |
| 7MS6 | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with… | x-ray diffraction | A | ZPV, SO4, ZN | — |
| 7MS7 | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with… | x-ray diffraction | A, B | ZN, ZQ1 | — |
| 7MS7 | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with… | x-ray diffraction | A, B | ZN, ZQ1 | — |
| P45974 | AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 5 (P45974) | — | — | — |
Ligands
- ZN · Zinc ion · in 10 records
- UNX · Unknown atom or ion · in 5 records
- CA · Calcium ion · in 2 records
- O4Y · (2R)-2-(4-oxoquinazolin-3(4H)-yl)propanoic acid · in 2 records
- ZOG · 4-{4-[4-(3,4-difluorophenyl)piperidine-1-sulfonyl]phenyl}-4-oxobutanoic acid · in 2 records
- ZQ1 · N-{5-[4-(4-chlorophenyl)piperidine-1-sulfonyl]pyridine-2-carbonyl}glycine · in 2 records
- HH4 · 4-(4-tert-butylphenyl)-4-oxobutanoic acid · in 1 record
- HHY · 3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanoic acid · in 1 record
- KKG · (4-oxoquinazolin-3(4H)-yl)acetic acid · in 1 record
- SO4 · Sulfate ion · in 1 record
- ZPV · N-[2-fluoro-4-(4-phenylpiperidine-1-sulfonyl) benzoyl]glycine · in 1 record
Elsewhere
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