UniProt P43873
Biotin carboxylase (P43873)
Biotin carboxylase (UniProt P43873), EC 6.3.4.14, 6.4.1.2: 20 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P43873
- Protein
- Biotin carboxylase
- EC
- 6.3.4.14, 6.4.1.2
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 1 · 1 record with a druggable one
Structures
21 records of P43873 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4MV1 | Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with ADP and… | x-ray diffraction | A | — | — |
| 4MV1 | Crystal structure of biotin carboxylase from haemophilus influenzae in complex with ADP and… | x-ray diffraction | A | — | — |
| 4MV3 | Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and… | x-ray diffraction | A | — | — |
| 4MV3 | Crystal structure of biotin carboxylase from haemophilus influenzae in complex with amppcp and… | x-ray diffraction | A | — | — |
| 4MV4 | Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and Mg2 | x-ray diffraction | A | — | — |
| 4MV4 | Crystal structure of biotin carboxylase from haemophilus influenzae in complex with amppcp and MG2 | x-ray diffraction | A | — | — |
| 4MV6 | Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with… | x-ray diffraction | A | — | — |
| 4MV6 | Crystal structure of biotin carboxylase from haemophilus influenzae in complex with… | x-ray diffraction | A | — | — |
| 4MV7 | Crystal Structure of Biotin Carboxylase form Haemophilus influenzae in Complex with Phosphonoformate | x-ray diffraction | A | — | — |
| 4MV7 | Crystal structure of biotin carboxylase form haemophilus influenzae in complex with phosphonoformate | x-ray diffraction | A | — | — |
| 4MV8 | Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and… | x-ray diffraction | A | — | — |
| 4MV8 | Crystal structure of biotin carboxylase from haemophilus influenzae in complex with amppcp and… | x-ray diffraction | A | — | — |
| 4MV9 | Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with Bicarbonate | x-ray diffraction | A | — | — |
| 4MV9 | Crystal structure of biotin carboxylase from haemophilus influenzae in complex with bicarbonate | x-ray diffraction | A | — | — |
| 4RZQ | Structural Analysis of Substrate, Reaction Intermediate and Product Binding in Haemophilus… | x-ray diffraction | A | — | — |
| 4RZQ | Structural analysis of substrate, reaction intermediate and product binding in haemophilus… | x-ray diffraction | A | — | — |
| 6OI8 | Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with… | x-ray diffraction | A | MQV | 1 (best 0.70) |
| 6OI8 | Crystal structure of haemophilus influenzae biotin carboxylase complexed with… | x-ray diffraction | A | MQV | — |
| 6OJH | Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with… | x-ray diffraction | A | MV4, CA | — |
| 6OJH | Crystal structure of haemophilus influenzae biotin carboxylase complexed with… | x-ray diffraction | A | MV4, CA | — |
| P43873 | AlphaFold monomer V2.0 prediction for biotin carboxylase (P43873) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4MV1 chain A against the predicted model P43873: TM-score 0.99, RMSD 0.62 Å
- 4MV1 chain A against the predicted model P43873: TM-score 0.99, RMSD 0.62 Å
- 4MV9 chain A against the predicted model P43873: TM-score 0.99, RMSD 0.68 Å
- 4MV9 chain A against the predicted model P43873: TM-score 0.99, RMSD 0.68 Å
- 6OI8 chain A against the predicted model P43873: TM-score 0.99, RMSD 0.82 Å
- 6OI8 chain A against the predicted model P43873: TM-score 0.99, RMSD 0.82 Å
- 6OJH chain A against the predicted model P43873: TM-score 0.99, RMSD 0.84 Å
- 6OJH chain A against the predicted model P43873: TM-score 0.99, RMSD 0.84 Å
- 4MV7 chain A against the predicted model P43873: TM-score 0.99, RMSD 0.85 Å
- 4MV7 chain A against the predicted model P43873: TM-score 0.99, RMSD 0.85 Å
Elsewhere
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