UniProt P43254
E3 ubiquitin-protein ligase COP1 (P43254)
E3 ubiquitin-protein ligase COP1 (UniProt P43254), EC 2.3.2.27: 21 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P43254
- Protein
- E3 ubiquitin-protein ligase COP1
- EC
- 2.3.2.27
- Experimental structures
- 21
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 9 · 5 records with a druggable one
Structures
22 records of P43254 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5IGO | WD40 domain of Arabidopsis thaliana E3 Ubiquitin Ligase COP1 in complex with peptide from Trib1 | x-ray diffraction | A, B, C, D | — | — |
| 5IGO | WD40 domain of arabidopsis thaliana E3 ubiquitin ligase COP1 in complex with peptide from TRIB1 | x-ray diffraction | A, B, C, D | — | — |
| 5KWN | The WD domain ofArabidopsis thaliana E3 Ubiquitin Ligase COP1 in complex with peptide from HY5 | x-ray diffraction | A | — | — |
| 5KWN | The wd domain ofarabidopsis thaliana E3 ubiquitin ligase COP1 in complex with peptide from HY5 | x-ray diffraction | A | — | — |
| 6QTO | Crystal structure of an Arabidopsis WD40 domain in complex with a transcription factor | x-ray diffraction | A | SO4 | 1 (best 0.77) |
| 6QTO | Crystal structure of an arabidopsis WD40 domain in complex with a transcription factor | x-ray diffraction | A | ACE, SO4 | — |
| 6QTQ | Crystal structure of an Arabidopsis WD40 domain in complex with photoreceptor | x-ray diffraction | A | SO4 | 2 (best 0.75) |
| 6QTQ | Crystal structure of an arabidopsis WD40 domain in complex with photoreceptor | x-ray diffraction | A | SO4 | — |
| 6QTR | Crystal structure of a mutant arabidopsis WD40 domain in complex with a transcription factor | x-ray diffraction | A | SO4 | — |
| 6QTS | Crystal structure of a mutant arabidopsis WD40 domain in complex with a photoreceptor | x-ray diffraction | A | SO4 | — |
| 6QTT | Crystal structure of an Arabidopsis WD40 domain in complex with a transcription factor homolog | x-ray diffraction | A | — | — |
| 6QTT | Crystal structure of an arabidopsis WD40 domain in complex with a transcription factor homolog | x-ray diffraction | A | — | — |
| 6QTU | Crystal structure of Arabidopsis WD40 domain in complex with a BBX transcription factor | x-ray diffraction | A | — | 2 (best 0.77) |
| 6QTU | Crystal structure of arabidopsis WD40 domain in complex with a bbx transcription factor | x-ray diffraction | A | — | — |
| 6QTV | Crystal structure of an Arabidopsis WD40 domain in complex with an atypical bHLH transcription… | x-ray diffraction | A | — | 2 (best 0.79) |
| 6QTV | Crystal structure of an arabidopsis WD40 domain in complex with an atypical bhlh transcription… | x-ray diffraction | A | — | — |
| 6QTW | Crystal structure of an Arabidopsis WD40 domain in complex with a blue light photoreceptor | x-ray diffraction | A | — | 2 (best 0.77) |
| 6QTW | Crystal structure of an arabidopsis WD40 domain in complex with a blue light photoreceptor | x-ray diffraction | A | — | — |
| 6QTX | Crystal structure of an arabidopsis WD40 domain in complex with a flowering transcription factor… | x-ray diffraction | A | SO4 | — |
| 7VGG | Cryo-EM structure of Ultraviolet-B activated UVR8 in complex with COP1 | electron microscopy | A | — | — |
| 7VGG | Cryo-EM structure of ultraviolet-B activated UVR8 in complex with COP1 | electron microscopy | A | — | — |
| P43254 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase COP1 (P43254) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6QTW chain A against the predicted model P43254: TM-score 1.00, RMSD 0.22 Å
- 6QTW chain A against the predicted model P43254: TM-score 1.00, RMSD 0.22 Å
- 6QTQ chain A against the predicted model P43254: TM-score 1.00, RMSD 0.33 Å
- 6QTQ chain A against the predicted model P43254: TM-score 1.00, RMSD 0.33 Å
- 6QTS chain A against the predicted model P43254: TM-score 1.00, RMSD 0.36 Å
- 5KWN chain A against the predicted model P43254: TM-score 1.00, RMSD 0.36 Å
- 5KWN chain A against the predicted model P43254: TM-score 1.00, RMSD 0.36 Å
- 6QTX chain A against the predicted model P43254: TM-score 1.00, RMSD 0.40 Å
- 6QTV chain A against the predicted model P43254: TM-score 1.00, RMSD 0.45 Å
- 6QTV chain A against the predicted model P43254: TM-score 1.00, RMSD 0.45 Å
Elsewhere
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