UniProt P38169
Kynurenine 3-monooxygenase (P38169)
Kynurenine 3-monooxygenase (UniProt P38169), EC 1.14.13.9: 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P38169
- Protein
- Kynurenine 3-monooxygenase
- EC
- 1.14.13.9
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 9 · 1 record with a druggable one
Structures
13 records of P38169 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4J2W | Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se) | x-ray diffraction | A, B | — | — |
| 4J2W | Crystal structure of kynurenine 3-monooxygenase (kmo-396PROT-se) | x-ray diffraction | A, B | — | — |
| 4J31 | Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot) | x-ray diffraction | A, B | — | — |
| 4J31 | Crystal structure of kynurenine 3-monooxygenase (kmo-396PROT) | x-ray diffraction | A, B | — | — |
| 4J33 | Crystal Structure of kynurenine 3-monooxygenase (KMO-394) | x-ray diffraction | A, B | — | — |
| 4J33 | Crystal structure of kynurenine 3-monooxygenase (kmo-394) | x-ray diffraction | A, B | — | — |
| 4J34 | Crystal Structure of kynurenine 3-monooxygenase - truncated at position 394 plus HIS tag cleaved. | x-ray diffraction | A, B | — | — |
| 4J34 | Crystal structure of kynurenine 3-monooxygenase - truncated at position 394 plus his tag cleaved. | x-ray diffraction | A, B | — | — |
| 4J36 | Cocrystal Structure of kynurenine 3-monooxygenase in complex with UPF 648 inhibitor(KMO-394UPF) | x-ray diffraction | A, B | — | — |
| 4J36 | Cocrystal structure of kynurenine 3-monooxygenase in complex with upf 648 INHIBITOR(KMO-394UPF) | x-ray diffraction | A, B | — | — |
| 5X6R | Crystal structure of Saccharomyces cerevisiae KMO in complex with Ro 61-8048 | x-ray diffraction | A, B | FAD, 7ZR | 9 (best 0.81) |
| 5X6R | Crystal structure of saccharomyces cerevisiae kmo in complex with ro 61-8048 | x-ray diffraction | A, B | FAD, 7ZR | — |
| P38169 | AlphaFold monomer V2.0 prediction for kynurenine 3-monooxygenase (P38169) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4J36 chain B against the predicted model P38169: TM-score 0.98, RMSD 1.05 Å
- 4J36 chain B against the predicted model P38169: TM-score 0.98, RMSD 1.05 Å
- 4J31 chain A against the predicted model P38169: TM-score 0.97, RMSD 1.28 Å
- 4J31 chain A against the predicted model P38169: TM-score 0.97, RMSD 1.28 Å
- 4J36 chain A against the predicted model P38169: TM-score 0.97, RMSD 1.46 Å
- 4J36 chain A against the predicted model P38169: TM-score 0.97, RMSD 1.46 Å
- 4J31 chain B against the predicted model P38169: TM-score 0.97, RMSD 1.60 Å
- 4J31 chain B against the predicted model P38169: TM-score 0.97, RMSD 1.60 Å
- 4J2W chain B against the predicted model P38169: TM-score 0.96, RMSD 1.63 Å
- 4J2W chain B against the predicted model P38169: TM-score 0.96, RMSD 1.63 Å
Elsewhere
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