UniProt P37571
Negative regulator of genetic competence ClpC/MecB (P37571)
Negative regulator of genetic competence ClpC/MecB (UniProt P37571): 20 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction…
- UniProt
- P37571
- Protein
- Negative regulator of genetic competence ClpC/MecB
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 1 · 0 records with a druggable one
Structures
21 records of P37571 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2K77 | NMR solution structure of the bacillus subtilis clpc N-domain | solution nmr | A | — | — |
| 2Y1Q | Crystal Structure of ClpC N-terminal Domain | x-ray diffraction | A | — | — |
| 2Y1Q | Crystal structure of clpc N-terminal domain | x-ray diffraction | A | — | — |
| 2Y1R | Structure of MecA121 & ClpC N-domain complex | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2Y1R | Structure of MECA121 & clpc N-domain complex | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3J3R | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | electron microscopy | A, B, C, D, E, F | — | — |
| 3J3R | Structural dynamics of the meca-clpc complex revealed by cryo-EM | electron microscopy | A, B, C, D, E, F | — | — |
| 3J3S | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | electron microscopy | A, B, C, D, E, F | — | — |
| 3J3S | Structural dynamics of the meca-clpc complex revealed by cryo-EM | electron microscopy | A, B, C, D, E, F | — | — |
| 3J3T | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | electron microscopy | A, B, C, D, E, F | — | — |
| 3J3T | Structural dynamics of the meca-clpc complex revealed by cryo-EM | electron microscopy | A, B, C, D, E, F | — | — |
| 3J3U | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | electron microscopy | A, B, C, D, E, F | — | — |
| 3J3U | Structural dynamics of the meca-clpc complex revealed by cryo-EM | electron microscopy | A, B, C, D, E, F | — | — |
| 3PXG | Structure of MecA121 and ClpC1-485 complex | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3PXG | Structure of MECA121 and CLPC1-485 complex | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3PXI | Structure of MecA108:ClpC | x-ray diffraction | A, B, C | — | — |
| 3PXI | Structure of MECA108:CLPC | x-ray diffraction | A, B, C | — | — |
| 5HBN | ClpC N-terminal domain with bound phospho-arginine | x-ray diffraction | A | SO4, RPI | 1 (best 0.27) |
| 5HBN | Clpc N-terminal domain with bound phospho-arginine | x-ray diffraction | A | — | — |
| 7ABR | Cryo-EM structure of B. subtilis clpc (dwb mutant) hexamer bound to a substrate polypeptide | electron microscopy | A, B, C, D, E, F | ADP, ATP | — |
| P37571 | AlphaFold monomer V2.0 prediction for negative regulator of genetic competence CLPC/MECB (P37571) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2Y1Q chain A against the predicted model P37571: TM-score 0.98, RMSD 0.81 Å
- 2Y1Q chain A against the predicted model P37571: TM-score 0.98, RMSD 0.81 Å
- 2Y1R chain F against the predicted model P37571: TM-score 0.97, RMSD 0.79 Å
- 2Y1R chain F against the predicted model P37571: TM-score 0.97, RMSD 0.79 Å
- 2Y1R chain B against the predicted model P37571: TM-score 0.97, RMSD 0.89 Å
- 2Y1R chain B against the predicted model P37571: TM-score 0.97, RMSD 0.89 Å
- 2Y1R chain C against the predicted model P37571: TM-score 0.97, RMSD 0.89 Å
- 2Y1R chain C against the predicted model P37571: TM-score 0.97, RMSD 0.89 Å
- 2Y1R chain E against the predicted model P37571: TM-score 0.97, RMSD 0.89 Å
- 2Y1R chain E against the predicted model P37571: TM-score 0.97, RMSD 0.89 Å
Elsewhere
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