UniProt P35956
Integrase (P35956)
Integrase (UniProt P35956), EC 2.7.7.-, 2.7.7.49: 16 experimental structures on GenesisL1, 3 ligands bound, 40 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P35956
- Protein
- Integrase
- EC
- 2.7.7.-, 2.7.7.49, 3.1.-.-, 3.1.13.2, 3.1.26.13, 3.4.23.-, 3.6.1.23
- Experimental structures
- 16
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 40 · 2 records with a druggable one
Structures
16 records of P35956 in the MolNFT archive: 16 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3HPG | Visna virus integrase (residues 1-219) in complex with LEDGF IBD: examples of open integrase… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3HPG | Visna virus integrase (residues 1-219) in complex with ledgf ibd: examples of open integrase… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3HPH | Closed tetramer of Visna virus integrase (residues 1-219) in complex with LEDGF IBD | x-ray diffraction | A, B, C, D | — | — |
| 3HPH | Closed tetramer of visna virus integrase (residues 1-219) in complex with ledgf ibd | x-ray diffraction | A, B, C, D | — | — |
| 5LLJ | Maedi-Visna virus (MVV) integrase C-terminal domain (residues 220-276) | x-ray diffraction | A, B | CL | — |
| 5LLJ | Maedi-visna virus (mvv) integrase C-terminal domain (residues 220-276) | x-ray diffraction | A, B | CL | — |
| 5M0Q | Cryo-EM reconstruction of the maedi-visna virus (mvv) intasome | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 5M0R | Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 5M0R | Cryo-EM reconstruction of the maedi-visna virus (mvv) strand transfer complex | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 5T3A | Maedi-Visna virus (MVV) integrase CCD-CTD (residues 60-275) | x-ray diffraction | A | — | — |
| 5T3A | Maedi-visna virus (mvv) integrase ccd-ctd (residues 60-275) | x-ray diffraction | A | — | — |
| 7U32 | Mvv cleaved synaptic complex (csc) intasome at 3.4 a resolution | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | ZN, CA | — |
| 7Z1Z | MVV strand transfer complex (STC) intasome in complex with LEDGF/p75 at 3.5 A resolution | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | ZN | 20 (best 0.87) |
| 7Z1Z | Mvv strand transfer complex (stc) intasome in complex with LEDGF/P75 at 3.5 a resolution | — | — | — | |
| 7ZPP | Cryo-EM structure of the MVV CSC intasome at 4.5A resolution | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | 20 (best 0.86) |
| 7ZPP | Cryo-EM structure of the mvv csc intasome at 4.5 a resolution | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
Ligands
Elsewhere
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