UniProt P35278
Ras-related protein Rab-5C (P35278)
Ras-related protein Rab-5C (UniProt P35278): 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35278
- Protein
- Ras-related protein Rab-5C
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 8 · 3 records with a druggable one
Structures
7 records of P35278 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HUQ | 1.8A crystal structure of the monomeric GTPase RAB5C (mouse) | x-ray diffraction | A | MG, GNP | 1 (best 0.49) |
| 1HUQ | 1.8A crystal structure of the monomeric GTPase RAB5C (mouse) | x-ray diffraction | A | — | — |
| 1Z07 | GppNHp-Bound Rab5c G55Q mutant GTPase | x-ray diffraction | A | MG, GNP | 1 (best 0.50) |
| 1Z07 | Gppnhp-bound RAB5C G55Q mutant GTPase | x-ray diffraction | A | — | — |
| 1Z0D | GDP-Bound Rab5c GTPase | x-ray diffraction | A, C | PO4, MG, GDP | 5 (best 0.74) |
| 1Z0D | GDP-bound RAB5C GTPase | x-ray diffraction | A, C | — | — |
| P35278 | AlphaFold monomer V2.0 prediction for RAS-related protein rab-5C (P35278) | predicted | A | — | 1 (best 0.55) |
Ligands
Experiment against prediction
- 1HUQ chain A against the predicted model P35278: TM-score 0.99, RMSD 0.48 Å
- 1HUQ chain A against the predicted model P35278: TM-score 0.99, RMSD 0.48 Å
- 1Z07 chain A against the predicted model P35278: TM-score 0.99, RMSD 0.57 Å
- 1Z07 chain A against the predicted model P35278: TM-score 0.99, RMSD 0.57 Å
- 1Z0D chain A against the predicted model P35278: TM-score 0.97, RMSD 1.01 Å
- 1Z0D chain A against the predicted model P35278: TM-score 0.97, RMSD 1.01 Å
Elsewhere
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