UniProt P34884
Macrophage migration inhibitory factor (P34884)
Macrophage migration inhibitory factor (UniProt P34884), EC 5.3.2.1: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P34884
- Protein
- Macrophage migration inhibitory factor
- EC
- 5.3.2.1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 6 records with a druggable one
Structures
7 records of P34884 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1MFF | Macrophage migration inhibitory factor Y95F mutant | x-ray diffraction | A, B, C | — | 2 (best 0.79) |
| 1MFF | Macrophage migration inhibitory factor Y95F mutant | x-ray diffraction | A, B, C | — | 2 (best 0.79) |
| 1MFI | Crystal structure of macrophage migration inhibitory factor complexed with… | x-ray diffraction | A, B, C | FHC | 3 (best 0.81) |
| 1MFI | Crystal structure of macrophage migration inhibitory factor complexed with… | x-ray diffraction | A, B, C | FHC | 3 (best 0.81) |
| 2GDG | Crystal structure of covalently modified macrophage inhibitory factor | x-ray diffraction | A, B, C | — | 4 (best 0.82) |
| 2GDG | Crystal structure of covalently modified macrophage inhibitory factor | x-ray diffraction | A, B, C | — | 4 (best 0.82) |
| P34884 | AlphaFold monomer V2.0 prediction for macrophage migration inhibitory factor (P34884) | predicted | A | — | — |
Ligands
- FHC · 2-fluoro-3-(4-hydroxyphenyl)-2E-propeneoate · in 2 records
Experiment against prediction
- 1MFI chain A against the predicted model P34884: TM-score 0.99, RMSD 0.35 Å
- 1MFI chain A against the predicted model P34884: TM-score 0.99, RMSD 0.35 Å
- 1MFF chain A against the predicted model P34884: TM-score 0.99, RMSD 0.36 Å
- 1MFF chain A against the predicted model P34884: TM-score 0.99, RMSD 0.36 Å
- 2GDG chain A against the predicted model P34884: TM-score 0.99, RMSD 0.39 Å
- 2GDG chain A against the predicted model P34884: TM-score 0.99, RMSD 0.39 Å
Elsewhere
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