UniProt P33734
Imidazole glycerol phosphate synthase hisHF (P33734)
Imidazole glycerol phosphate synthase hisHF (UniProt P33734), EC 2.4.2.-, 4.1.3.-: 8 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 43 pockets. Binding sites, druggability and experiment against…
- UniProt
- P33734
- Protein
- Imidazole glycerol phosphate synthase hisHF
- EC
- 2.4.2.-, 4.1.3.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 43 · 4 records with a druggable one
Structures
9 records of P33734 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JVN | Crystal structure of imidazole glycerol phosphate synthase: a tunnel through a (BETA/ALPHA)8 barrel… | x-ray diffraction | A, B | NI, SO4, POP | 14 (best 0.77) |
| 1JVN | Crystal structure of imidazole glycerol phosphate synthase: a tunnel through a (BETA/ALPHA)8 barrel… | x-ray diffraction | A, B | — | — |
| 1OX4 | Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole… | x-ray diffraction | A, B | SO4, NI, POP | 9 (best 0.76) |
| 1OX4 | Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole… | x-ray diffraction | A, B | — | — |
| 1OX5 | Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole… | x-ray diffraction | A, B | NI, 1PR | 13 (best 0.76) |
| 1OX5 | Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole… | x-ray diffraction | A, B | — | — |
| 1OX6 | Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole… | x-ray diffraction | A, B | NI, SO4, POP | 7 (best 0.80) |
| 1OX6 | Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole… | x-ray diffraction | A, B | — | — |
| P33734 | AlphaFold monomer V2.0 prediction for imidazole glycerol phosphate synthase hishf (P33734) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1OX5 chain B against the predicted model P33734: TM-score 1.00, RMSD 0.37 Å
- 1OX5 chain B against the predicted model P33734: TM-score 1.00, RMSD 0.37 Å
- 1OX6 chain A against the predicted model P33734: TM-score 0.99, RMSD 0.27 Å
- 1OX6 chain A against the predicted model P33734: TM-score 0.99, RMSD 0.27 Å
- 1JVN chain A against the predicted model P33734: TM-score 0.99, RMSD 0.43 Å
- 1JVN chain A against the predicted model P33734: TM-score 0.99, RMSD 0.43 Å
- 1OX5 chain A against the predicted model P33734: TM-score 0.99, RMSD 0.44 Å
- 1OX5 chain A against the predicted model P33734: TM-score 0.99, RMSD 0.44 Å
- 1OX4 chain A against the predicted model P33734: TM-score 0.99, RMSD 0.45 Å
- 1OX4 chain A against the predicted model P33734: TM-score 0.99, RMSD 0.45 Å
Elsewhere
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