UniProt P33672
Proteasome subunit beta type-3 (P33672)
Proteasome subunit beta type-3 (UniProt P33672), EC 3.4.25.1: 9 experimental structures and 1 predicted model on GenesisL1, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P33672
- Protein
- Proteasome subunit beta type-3
- EC
- 3.4.25.1
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 23 · 4 records with a druggable one
Structures
10 records of P33672 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IRU | Crystal Structure of the mammalian 20S proteasome at 2.75 A resolution | x-ray diffraction | J, X | — | — |
| 1IRU | Crystal structure of the mammalian 20S proteasome at 2.75 a resolution | x-ray diffraction | J, X | — | — |
| 7DR6 | PA28ALPHA-beta in complex with immunoproteasome | electron microscopy | H, S | — | — |
| 7DR7 | bovine 20S immunoproteasome | electron microscopy | H, S | — | 6 (best 0.81) |
| 7DR7 | Bovine 20S immunoproteasome | electron microscopy | H, S | — | — |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28ALPHA-beta activators | electron microscopy | k, S | — | — |
| 8AZK | Bovine 20S proteasome, untreated | electron microscopy | J, X | — | 6 (best 0.79) |
| 8FZ5 | The PI31-free Bovine 20S proteasome | electron microscopy | J, X | — | 6 (best 0.80) |
| 8FZ6 | The human PI31 complexed with bovine 20S proteasome | electron microscopy | J, X | — | 5 (best 0.80) |
| P33672 | AlphaFold monomer V2.0 prediction for proteasome subunit beta type-3 (P33672) | predicted | A | — | — |
Experiment against prediction
- 8FZ5 chain X against the predicted model P33672: TM-score 1.00, RMSD 0.22 Å
- 8FZ5 chain J against the predicted model P33672: TM-score 1.00, RMSD 0.22 Å
- 8FZ6 chain J against the predicted model P33672: TM-score 1.00, RMSD 0.25 Å
- 8FZ6 chain X against the predicted model P33672: TM-score 1.00, RMSD 0.26 Å
- 1IRU chain J against the predicted model P33672: TM-score 1.00, RMSD 0.34 Å
- 1IRU chain J against the predicted model P33672: TM-score 1.00, RMSD 0.34 Å
- 7DR7 chain S against the predicted model P33672: TM-score 0.99, RMSD 0.55 Å
- 7DR7 chain H against the predicted model P33672: TM-score 0.99, RMSD 0.56 Å
- 7DR7 chain H against the predicted model P33672: TM-score 0.99, RMSD 0.56 Å
- 8AZK chain X against the predicted model P33672: TM-score 0.98, RMSD 0.69 Å
Elsewhere
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