UniProt P32835
GTP-binding nuclear protein GSP1/CNR1 (P32835)
GTP-binding nuclear protein GSP1/CNR1 (UniProt P32835): 11 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32835
- Protein
- GTP-binding nuclear protein GSP1/CNR1
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 25 · 3 records with a druggable one
Structures
12 records of P32835 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2X19 | Crystal structure of Importin13 - RanGTP complex | x-ray diffraction | A | — | — |
| 2X19 | Crystal structure of IMPORTIN13 - rangtp complex | x-ray diffraction | A | — | — |
| 3ICQ | Karyopherin nuclear state | x-ray diffraction | B, C | — | — |
| 3ICQ | Karyopherin nuclear state | x-ray diffraction | B, C | — | — |
| 3M1I | Crystal structure of yeast CRM1 (Xpo1p) in complex with yeast RanBP1 (Yrb1p) and yeast RanGTP… | x-ray diffraction | A | — | — |
| 3M1I | Crystal structure of yeast CRM1 (XPO1P) in complex with yeast RANBP1 (YRB1P) and yeast rangtp… | x-ray diffraction | A | — | — |
| 8DYO | Cryo-EM structure of Importin-4 bound to RanGTP | electron microscopy | B | MG, GTP | — |
| 8F19 | Cryo-EM structure of Kap114 bound to Gsp1 (RanGTP) | electron microscopy | B | GTP, MG | 6 (best 0.77) |
| 8F1E | Cryo-EM structure of Kap114 bound to Gsp1 (RanGTP) and H2A-H2B | electron microscopy | D | MG, GTP | — |
| 8F7A | Cryo-EM structure of Importin-9 bound to RanGTP | electron microscopy | B | MG, GTP | 4 (best 0.77) |
| 8QYZ | Crystal structure of hiNES2 in complex with Xpo1 and RanGTP | x-ray diffraction | A, B, E, G | GTP, MG | 15 (best 0.87) |
| P32835 | AlphaFold monomer V2.0 prediction for GTP-binding nuclear protein GSP1/CNR1 (P32835) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8QYZ chain G against the predicted model P32835: TM-score 0.98, RMSD 0.63 Å
- 8QYZ chain E against the predicted model P32835: TM-score 0.98, RMSD 0.65 Å
- 3ICQ chain B against the predicted model P32835: TM-score 0.98, RMSD 0.66 Å
- 3ICQ chain B against the predicted model P32835: TM-score 0.98, RMSD 0.66 Å
- 8QYZ chain B against the predicted model P32835: TM-score 0.98, RMSD 0.82 Å
- 3ICQ chain C against the predicted model P32835: TM-score 0.98, RMSD 0.67 Å
- 3ICQ chain C against the predicted model P32835: TM-score 0.98, RMSD 0.67 Å
- 8QYZ chain A against the predicted model P32835: TM-score 0.98, RMSD 0.83 Å
- 8F1E chain D against the predicted model P32835: TM-score 0.98, RMSD 0.74 Å
- 8F19 chain B against the predicted model P32835: TM-score 0.98, RMSD 0.85 Å
Elsewhere
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