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UniProt P32582

Cystathionine beta-synthase (P32582)

Cystathionine beta-synthase (UniProt P32582), EC 4.2.1.22: 5 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P32582
Protein
Cystathionine beta-synthase
EC
4.2.1.22
Experimental structures
5
Predicted models
1
Ligands
6
Pockets
3 · 1 record with a druggable one

Structures

6 records of P32582 in the MolNFT archive: 5 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6C2HCrystal structures of cystathionine beta-synthase from saccharomyces cerevisiae: the structure of…x-ray diffractionAPLP, CA, NA, CL—
6C2QCrystal Structures of Cystathionine beta-Synthase from Saccharomyces cerevisiae: the Structure of…x-ray diffractionAEVM, CA, NA, CL3 (best 0.76)
6C2QCrystal structures of cystathionine beta-synthase from saccharomyces cerevisiae: the structure of…x-ray diffractionACA, NA, CL—
6C2ZCrystal structures of cystathionine beta-synthase from saccharomyces cerevisiae: the structure of…x-ray diffractionACA, NA, CL—
6C4PCrystal structures of cystathionine beta-synthase from saccharomyces cerevisiae: the structure of…x-ray diffractionAPMP, CA, NA, CL—
P32582AlphaFold monomer V2.0 prediction for cystathionine beta-synthase (P32582)predictedA——

Ligands

  • CA · Calcium ion · in 5 records
  • CL · Chloride ion · in 5 records
  • NA · Sodium ion · in 5 records
  • EVM · L-Serine, N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methylene] · in 1 record
  • PLP · Pyridoxal-5'-phosphate · in 1 record
  • PMP · 4'-deoxy-4'-aminopyridoxal-5'-phosphate · in 1 record

Experiment against prediction

Elsewhere

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