UniProt P32561
Histone deacetylase RPD3 (P32561)
Histone deacetylase RPD3 (UniProt P32561), EC 3.5.1.98: 14 experimental structures on GenesisL1, 4 ligands bound, 96 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P32561
- Protein
- Histone deacetylase RPD3
- EC
- 3.5.1.98
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 96 · 13 records with a druggable one
Structures
14 records of P32561 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7YI2 | Cryo-EM structure of Rpd3S in loose-state Rpd3S-NCP complex | electron microscopy | B | ZN | 9 (best 0.82) |
| 7YI4 | Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in close state | electron microscopy | B | ZN | 7 (best 0.74) |
| 7YI5 | Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in loose state | electron microscopy | B | ZN | 6 (best 0.80) |
| 8HPO | Cryo-EM structure of a SIN3/HDAC complex from budding yeast | electron microscopy | F, G | TPO, ZN, K | 12 (best 0.86) |
| 8HXX | Cryo-EM structure of the histone deacetylase complex Rpd3S | electron microscopy | L | ZN | 9 (best 0.83) |
| 8IHT | Rpd3S bound to the nucleosome | electron microscopy | L | ZN, CA | 7 (best 0.81) |
| 8KC7 | Rpd3S histone deacetylase complex | electron microscopy | A | — | 8 (best 0.79) |
| 8KD3 | Rpd3S in complex with nucleosome with H3K36MLA modification, H3K9Q mutation and 187bp DNA | electron microscopy | A | ZN | 6 (best 0.83) |
| 8KD5 | Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class2 | electron microscopy | A | ZN | 6 (best 0.81) |
| 8TOF | Rpd3S bound to an H3K36Cme3 modified nucleosome | electron microscopy | B | ZN | 6 (best 0.81) |
| 8W9C | Cryo-EM structure of the Rpd3S complex from budding yeast | electron microscopy | B | ZN, K | 9 (best 0.79) |
| 8W9D | Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 1 | electron microscopy | B | ZN, K | 5 (best 0.83) |
| 8W9F | Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 3 | electron microscopy | B | ZN | 6 (best 0.79) |
| P32561 | AlphaFold monomer V2.0 prediction for histone deacetylase RPD3 (P32561) | — | — | — |
Ligands
Elsewhere
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