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Ligand · TPO

TPO · Phosphothreonine

TPO, Phosphothreonine (C4 H10 N O6 P, 199.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
TPO
Formula
C4 H10 N O6 P
Class
ligand
Structures
2
PDB entries
2

Binding sites

TPO in 2 structures; the first of them:

  • 6QDU · Crystal structure of 14-3-3sigma in complex with a RapGef2 pT740 phosphopeptide inhibited… · TPO A302 · binds LYS49, ARG56, ARG129, TYR130, LEU174, ASN175, VAL178, LEU222
  • 8HPO · Cryo-EM structure of a SIN3/HDAC complex from budding yeast · TPO F501 · binds GLN263, PRO264, SEP265, ILE303, ASN392, HIS393, GLU202

Residues it binds most

ARG 1, ASN 2, LEU 1, GLN 1, GLU 1, HIS 1, ILE 1, LYS 1, PRO 1, SEP 1 (residue and the binding sites it lines).

Found with

  • HY5 · Fc-ncpc
  • K · Potassium ion
  • NA · Sodium ion
  • ZN · Zinc ion
  • CL · Chloride ion

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