UniProt P32456
Guanylate-binding protein 2 (P32456)
Guanylate-binding protein 2 (UniProt P32456), EC 3.6.5.-: 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32456
- Protein
- Guanylate-binding protein 2
- EC
- 3.6.5.-
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 8 · 1 record with a druggable one
Structures
6 records of P32456 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6VKJ | Crystal structure of the G domain of human guanylate-binding protein 2 (HGBP2) in complex with GDP | x-ray diffraction | A | GDP | — |
| 7E58 | interferon-inducible anti-viral protein 2 | x-ray diffraction | A, B | — | — |
| 7E58 | Interferon-inducible anti-viral protein 2 | x-ray diffraction | A, B | — | — |
| 7M1S | Crystal structure of human guanylate-binding protein 2 (hGBP2) K51A mutant | x-ray diffraction | A | PO4 | 8 (best 0.71) |
| 7M1S | Crystal structure of human guanylate-binding protein 2 (HGBP2) K51A mutant | x-ray diffraction | A | PO4 | — |
| P32456 | AlphaFold monomer V2.0 prediction for guanylate-binding protein 2 (P32456) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7E58 chain B against the predicted model P32456: TM-score 0.98, RMSD 1.15 Å
- 7E58 chain B against the predicted model P32456: TM-score 0.98, RMSD 1.15 Å
- 7E58 chain A against the predicted model P32456: TM-score 0.97, RMSD 1.43 Å
- 7E58 chain A against the predicted model P32456: TM-score 0.97, RMSD 1.43 Å
- 7M1S chain A against the predicted model P32456: TM-score 0.95, RMSD 2.17 Å
- 7M1S chain A against the predicted model P32456: TM-score 0.95, RMSD 2.17 Å
- 6VKJ chain A against the predicted model P32456: TM-score 0.88, RMSD 2.80 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.