UniProt P32246
C-C chemokine receptor type 1 (P32246)
C-C chemokine receptor type 1 (UniProt P32246): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 28 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32246
- Protein
- C-C chemokine receptor type 1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 28 · 7 records with a druggable one
Structures
7 records of P32246 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7VL8 | Cryo-EM structure of the Apo CCR1-Gi complex | electron microscopy | R | CLR | 4 (best 0.72) |
| 7VL8 | Cryo-EM structure of the apo CCR1-gi complex | electron microscopy | R | CLR | 4 (best 0.72) |
| 7VL9 | Cryo-EM structure of the CCL15(26-92) bound CCR1-Gi complex | electron microscopy | R | CLR | 4 (best 0.85) |
| 7VL9 | Cryo-EM structure of the CCL15(26-92) bound CCR1-gi complex | electron microscopy | R | CLR | 4 (best 0.85) |
| 7VLA | Cryo-EM structure of the CCL15(27-92) bound CCR1-Gi complex | electron microscopy | R | CLR | 5 (best 0.85) |
| 7VLA | Cryo-EM structure of the CCL15(27-92) bound CCR1-gi complex | electron microscopy | R | CLR | 5 (best 0.85) |
| P32246 | AlphaFold monomer V2.0 prediction for C-C chemokine receptor type 1 (P32246) | predicted | A | — | 2 (best 0.76) |
Ligands
- CLR · Cholesterol · in 6 records
Experiment against prediction
- 7VL8 chain R against the predicted model P32246: TM-score 0.93, RMSD 2.02 Å
- 7VL8 chain R against the predicted model P32246: TM-score 0.93, RMSD 2.02 Å
- 7VL9 chain R against the predicted model P32246: TM-score 0.93, RMSD 2.08 Å
- 7VL9 chain R against the predicted model P32246: TM-score 0.93, RMSD 2.08 Å
- 7VLA chain R against the predicted model P32246: TM-score 0.93, RMSD 2.08 Å
- 7VLA chain R against the predicted model P32246: TM-score 0.93, RMSD 2.08 Å
Elsewhere
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