UniProt P30822
Exportin-1 (P30822)
Exportin-1 (UniProt P30822): 96 experimental structures on GenesisL1, 10 ligands bound, 69 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P30822
- Protein
- Exportin-1
- Experimental structures
- 96
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 69 · 6 records with a druggable one
Structures
96 records of P30822 in the MolNFT archive: 96 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3M1I | Crystal structure of yeast CRM1 (Xpo1p) in complex with yeast RanBP1 (Yrb1p) and yeast RanGTP… | x-ray diffraction | C | — | — |
| 3M1I | Crystal structure of yeast CRM1 (XPO1P) in complex with yeast RANBP1 (YRB1P) and yeast rangtp… | x-ray diffraction | C | — | — |
| 3VYC | Crystal structure of unliganded Saccharomyces cerevisiae CRM1 (Xpo1p) | x-ray diffraction | A | — | — |
| 3VYC | Crystal structure of unliganded saccharomyces cerevisiae CRM1 (XPO1P) | x-ray diffraction | A | — | — |
| 3WYF | Crystal structure of Xpo1p-Yrb2p-Gsp1p-GTP complex | x-ray diffraction | C, F | — | — |
| 3WYF | Crystal structure of XPO1P-YRB2P-GSP1P-GTP complex | x-ray diffraction | C, F | — | — |
| 3WYG | Crystal structure of Xpo1p-PKI-Gsp1p-GTP complex | x-ray diffraction | C | — | — |
| 3WYG | Crystal structure of XPO1P-pki-GSP1P-GTP complex | x-ray diffraction | C | — | — |
| 4GMX | Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4GMX | Crystal structure of KPT185 in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 4GPT | Crystal structure of KPT251 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4GPT | Crystal structure of KPT251 in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 4HAT | Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4HAT | Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1- ran-RANBP1 | x-ray diffraction | C | — | — |
| 4HAU | Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4HAU | Crystal structure of CRM1 inhibitor ratjadone a in complex with CRM1- ran-RANBP1 | x-ray diffraction | C | — | — |
| 4HAV | Crystal structure of CRM1 inhibitor Anguinomycin A in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4HAV | Crystal structure of CRM1 inhibitor anguinomycin a in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 4HAW | Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548A)-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4HAW | Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1(K548A)-ran-RANBP1 | x-ray diffraction | C | — | — |
| 4HAX | Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1(K579A)-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4HAX | Crystal structure of CRM1 inhibitor ratjadone a in complex with CRM1(K579A)-ran-RANBP1 | x-ray diffraction | C | — | — |
| 4HAY | Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548E,K579Q)-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4HAY | Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1(K548E,K579Q)-ran-RANBP1 | x-ray diffraction | C | — | — |
| 4HAZ | Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(R543S,K548E,K579Q)-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4HAZ | Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1(R543S,K548E,K579Q)-ran-RANBP1 | x-ray diffraction | C | — | — |
| 4HB0 | Crystal structure of CRM1 inhibitor Leptomycin B in complex with… | x-ray diffraction | C | — | — |
| 4HB0 | Crystal structure of CRM1 inhibitor leptomycin B in complex with… | x-ray diffraction | C | — | — |
| 4HB2 | Crystal structure of CRM1-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4HB2 | Crystal structure of CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 4HB3 | Crystal structure of CRM1(T539S)-Ran-RanBP1 with weakly bound unmodeled Leptomycin B | x-ray diffraction | C | — | — |
| 4HB3 | Crystal structure of CRM1(T539S)-ran-RANBP1 with weakly bound unmodeled leptomycin B | x-ray diffraction | C | — | — |
| 4HB4 | Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 4HB4 | Crystal structure of CRM1 inhibitor leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5DH9 | Crystal Structure of PKI NES Flip Mutant Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | — | 10 (best 0.85) |
| 5DH9 | Crystal structure of pki nes flip mutant peptide in complex with CRM1- ran-RANBP1 | x-ray diffraction | C | — | — |
| 5DHA | Crystal structure of CPEB4 nes reverse mutant peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5DHF | Crystal structure of HRIO2 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5DI9 | Crystal structure of HRIO2 nes reverse mutant peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5DIF | Crystal structure of CPEB4 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5JLJ | Crystal Structure of KPT8602 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | 6L8 | — |
| 5JLJ | Crystal structure of KPT8602 in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5UWH | Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 5UWH | Crystal structure of paxillin nes peptide in complex with CRM1-ran- RANBP1 | x-ray diffraction | C | — | — |
| 5UWI | Crystal Structure of HDAC5 NES Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 5UWI | Crystal structure of HDAC5 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5UWJ | Crystal Structure of FMRP NES Peptide in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | — | 10 (best 0.85) |
| 5UWJ | Crystal structure of fmrp nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5UWO | Crystal structure of engineered fmrp-1B nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5UWP | Crystal structure of MDIA2 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5UWQ | Crystal structure of CDC7 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5UWR | Crystal structure of CDC7 nes peptide (extended) in complex with CRM1- ran-RANBP1 | x-ray diffraction | C | CL | — |
| 5UWS | Crystal structure of X11L2 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | — | — |
| 5UWT | Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1 | x-ray diffraction | C | — | — |
| 5UWT | Crystal structure of HXK2 peptide in complex with CRM1 K579A mutant- ran-RANBP1 | x-ray diffraction | C | — | — |
| 5UWU | Crystal structure of SMAD4 nes peptide in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | CL | — |
| 5UWW | Crystal structure of DEAF1 peptide in complex with CRM1 K579A mutant- ran-RANBP1 | x-ray diffraction | C | — | — |
| 5XOJ | Crystal structure of XPO1P-pki-NUP42P-GSP1P-GTP complex | x-ray diffraction | C | — | — |
| 5YRO | RANL182A in complex with RANBP1-CRM1 | x-ray diffraction | C | CL | — |
| 5YST | RANM189D in complex with RANBP1-CRM1 | x-ray diffraction | C | CL | — |
36 records more on the page itself.
Ligands
- CL · Chloride ion · in 12 records
- NA · Sodium ion · in 6 records
- NO3 · Nitrate ion · in 4 records
- 6L8 · (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide · in 3 records
- F2X · (2~{R})-2-methyl-5-oxidanyl-2,3-dihydronaphthalene-1,4-dione · in 3 records
- V6A · selinexor, bound form · in 3 records
- K85 · Propan-2-yl 3-{3-[3-methoxy-5-(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}propanoate · in 2 records
- D29 · (Z)-{[(3E)-4-{(R)-[3,5-bis(trifluoromethyl) phenyl]sulfinyl}but-3-en-1-yl]imino}methanethiol · in 1 record
- EQF · (3~{R},4~{S})-1-[[6-chloranyl-5-(trifluoromethyl) pyridin-2-yl]amino]-3,4-dimethyl-pyrrolidine-2,5-dione · in 1 record
- ODN · (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14r, 16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one · in 1 record
Elsewhere
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