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Ligand · LBF

LBF · Leptomycin B

LBF, Leptomycin B (C33 H48 O6, 540.7 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
LBF
Formula
C33 H48 O6
Class
ligand
Structures
4
PDB entries
2

Binding sites

LBF in 4 structures; the first of them:

  • 4HAZ · Crystal structure of CRM1 inhibitor Leptomycin B in complex with… · LBF C1101 · binds LYS525, VAL529, ILE532, LYS533, LEU536, CYS539, GLU548, VAL551 and 13 more
  • 4HB0 · Crystal structure of CRM1 inhibitor Leptomycin B in complex with… · LBF C1101 · binds LYS525, VAL529, ILE532, LYS533, LEU536, CYS539, GLN548, VAL551 and 13 more
  • 4HAZ · Crystal structure of CRM1 inhibitor leptomycin B in complex with… · LBF C1101 · binds LYS525, VAL529, ILE532, LYS533, LEU536, CYS539, GLU548, VAL551 and 13 more
  • 4HB0 · Crystal structure of CRM1 inhibitor leptomycin B in complex with… · LBF C1101 · binds LYS525, VAL529, ILE532, LYS533, LEU536, CYS539, GLN548, VAL551 and 13 more

Residues it binds most

VAL 4, PHE 4, ILE 4, LEU 4, LYS 4, GLN 4, ALA 4, ASN 4, CYS 4, HIS 4 (residue and the binding sites it lines).

Found with

  • GNP · Phosphoaminophosphonic acid-guanylate ester
  • MG · Magnesium ion
  • CL · Chloride ion

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