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Ligand · EQF

EQF · (3~{R},4~{S})-1-[[6-chloranyl-5-(trifluoromethyl) pyridin-2-yl]amino]-3,4-dimethyl-pyrrolidine-2,5-dione

EQF, (3~{R},4~{S})-1-[[6-chloranyl-5-(trifluoromethyl) pyridin-2-yl]amino]-3,4-dimethyl-pyrrolidine-2,5-dione (C12 H11 Cl F3 N3 O2, 321.7 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site…

Component
EQF
Formula
C12 H11 Cl F3 N3 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

EQF in 1 structure; the first of them:

  • 6LQ9 · S109 in complex with CRM1-ran-RANBP1 · EQF C1101 · binds LEU536, CYS539, LYS548, VAL551, ALA552, ILE555, THR575, VAL576 and 2 more

Residues it binds most

LYS 1, VAL 1, ALA 1, CYS 1, ILE 1, LEU 1, PHE 1, THR 1 (residue and the binding sites it lines).

Found with

  • GTP · Guanosine-5'-triphosphate
  • MG · Magnesium ion
  • CL · Chloride ion
  • NO3 · Nitrate ion
  • GOL · Glycerol

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