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UniProt P29972

Aquaporin-1 (P29972)

Aquaporin-1 (UniProt P29972): 16 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 34 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P29972
Protein
Aquaporin-1
Experimental structures
16
Predicted models
1
Ligands
1
Pockets
34 · 4 records with a druggable one

Structures

17 records of P29972 in the MolNFT archive: 16 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
1FQYStructure of aquaporin-1 at 3.8 a resolution by electron crystallographyelectron crystallographyA——
1FQYStructure of aquaporin-1 at 3.8 a resolution by electron crystallographyelectron crystallographyA——
1H6IA refined structure of human aquaporin 1electron crystallographyA——
1H6IA refined structure of human aquaporin 1electron crystallographyA——
1IH5Crystal structure of aquaporin-1electron crystallographyA——
1IH5Crystal structure of aquaporin-1electron crystallographyA——
4CSKhuman Aquaporinx-ray diffractionA——
4CSKHuman aquaporinx-ray diffractionA——
6POJStructural refinement of aquaporin 1 via ssnmrsolid-state nmrA—5 (best 0.54)
6POJStructural refinement of aquaporin 1 via ssnmrsolid-state nmrA——
7UZEErythrocyte ankyrin-1 complex class 2 local refinement of AQP1 (C4 symmetry applied)electron microscopyD, B, C, ACLR12 (best 0.83)
7UZEErythrocyte ankyrin-1 complex class 2 local refinement of AQP1 (C4 symmetry applied)electron microscopyD, B, C, ACLR—
8CT2Local refinement of AQP1 tetramer (C1; refinement mask included D1 of protein 4.2 and Ankyrin-1…electron microscopyD, B, C, ACLR13 (best 0.84)
8CT2Local refinement of AQP1 tetramer (C1; refinement mask included D1 of protein 4.2 and ankyrin-1…electron microscopyD, B, C, ACLR—
8CTEClass 2 of erythrocyte ankyrin-1 complex (Composite map)electron microscopyS, O, R, MCLR4 (best 0.84)
8CTEClass 2 of erythrocyte ankyrin-1 complex (composite MAP)electron microscopyS, O, R, MCLR—
P29972AlphaFold monomer V2.0 prediction for aquaporin-1 (P29972)predictedA——

Ligands

  • CLR · Cholesterol · in 6 records

Experiment against prediction

Elsewhere

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