MolNFT v1 · #88369 · protein

Human aquaporin

4CSK · Aquaporin-1: “Human aquaporin”. X-ray diffraction, 2 pockets (best druggability 0.48). MolNFT v1 #88369 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4CSK
Type: protein
Length: 233 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aquaporin-1
UniProt: P29972
Pockets: 2 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 55% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aquaporin-1	protein	233	55% helix, 0% strand	P29972

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	127	0.48	0.78	24	empty
2	118	0.47	0.79	26	empty

Compared structures

4CSK · human Aquaporin · the same entry in another collection · chain A against A, TM-score 1.00
P29972 · AlphaFold monomer V2.0 prediction for aquaporin-1 (P29972) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29972
Elsewhere: RCSB PDB 4CSK · PDBe 4CSK · UniProt P29972

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.