UniProt P29068

Carboxypeptidase T (P29068)

Carboxypeptidase T (UniProt P29068), EC 3.4.17.18: 45 experimental structures and 1 predicted model on GenesisL1, 9 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P29068
Protein: Carboxypeptidase T
EC: 3.4.17.18
Experimental structures: 45
Predicted models: 1
Ligands: 9
Pockets: 9 · 7 records with a druggable one

Structures

46 records of P29068 in the MolNFT archive: 45 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
1OBR	Carboxypeptidase T	x-ray diffraction	A	—	—
1OBR	Carboxypeptidase T	x-ray diffraction	A	—	—
3PRT	Mutant of the Carboxypeptidase T	x-ray diffraction	A	—	—
3PRT	Mutant of the carboxypeptidase T	x-ray diffraction	A	—	—
3QNV	Carboxypeptidase T	x-ray diffraction	A	—	—
3QNV	Carboxypeptidase T	x-ray diffraction	A	—	—
3V38	Carboxypeptidase T mutant L254N	x-ray diffraction	A	—	—
3V38	Carboxypeptidase T mutant L254N	x-ray diffraction	A	—	—
3V7Z	Carboxypeptidase T with GEMSA	x-ray diffraction	A	—	—
3V7Z	Carboxypeptidase T with gemsa	x-ray diffraction	A	—	—
4DJL	Carboxypeptidase T with N-sulfamoyl-L-phenylalanine	x-ray diffraction	A	—	—
4DJL	Carboxypeptidase T with N-sulfamoyl-L-phenylalanine	x-ray diffraction	A	—	—
4DUK	Carboxypeptidase T with L-BENZYLSUCCINIC ACID	x-ray diffraction	A	—	—
4DUK	Carboxypeptidase T with L-benzylsuccinic acid	x-ray diffraction	A	—	—
4F8Z	Carboxypeptidase T with Boc-Leu	x-ray diffraction	A	—	—
4F8Z	Carboxypeptidase T with boc-leu	x-ray diffraction	A	—	—
4GM5	Carboxypeptidase T with Sulphamoil Arginine	x-ray diffraction	A	—	—
4GM5	Carboxypeptidase T with sulphamoil arginine	x-ray diffraction	A	—	—
4IAV	G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with…	x-ray diffraction	A	—	—
4IAV	G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from thermoactinomyces vulgaris with…	x-ray diffraction	A	—	—
4IHM	G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris	x-ray diffraction	A	—	—
4IHM	G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from thermoactinomyces vulgaris	x-ray diffraction	A	—	—
4IK2	G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with…	x-ray diffraction	A	—	—
4IK2	G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from thermoactinomyces vulgaris with…	x-ray diffraction	A	—	—
6F6Q	Carboxypeptidase T mutant L254N with Sulphamoil Arginine	x-ray diffraction	A	ZN, CA, SO4, 0X9	2 (best 0.54)
6F6Q	Carboxypeptidase T mutant L254N with sulphamoil arginine	x-ray diffraction	A	ZN, CA, SO4, 0X9	—
6F75	Carboxypeptidase T mutant L254N with Sulphamoil Leucine	x-ray diffraction	A	ZN, CA, SO4, LU0	—
6F75	Carboxypeptidase T mutant L254N with sulphamoil leucine	x-ray diffraction	A	ZN, CA, SO4, LU0	—
6F79	Carboxypeptidase T mutant L211Q with Sulphamoil Arginine	x-ray diffraction	A	ZN, CA, SO4, 0X9	1 (best 0.53)
6F79	Carboxypeptidase T mutant L211Q with sulphamoil arginine	x-ray diffraction	A	ZN, CA, SO4, 0X9	—
6GO2	Carboxypeptidase T with N-sulfamoyl-L-Leucine	x-ray diffraction	A	ZN, CA, SO4, LU0	1 (best 0.56)
6GO2	Carboxypeptidase T with N-sulfamoyl-L-leucine	x-ray diffraction	A	ZN, CA, SO4, LU0	—
6Q4L	Carboxypeptidase T mutant L254N with with N-sulfamoyl-L-glutamic acid	x-ray diffraction	A	ZN, CA, SO4	—
6SN6	Carboxypeptidase T with N-sulfamoyl-L-glutamic acid	x-ray diffraction	A	ZN, 3K0, CA	1 (best 0.56)
6SN6	Carboxypeptidase T with N-sulfamoyl-L-glutamic acid	x-ray diffraction	A	ZN, CA	—
6T9Y	Carboxypeptidase T with N-sulfamoyl-L-lysin	x-ray diffraction	A	7B0, ZN, CA	1 (best 0.56)
6T9Y	Carboxypeptidase T with N-sulfamoyl-L-lysin	x-ray diffraction	A	7B0, ZN, CA	—
6TNK	Carboxypeptidase T with N-sulfamoyl-L-valine	x-ray diffraction	A	ZN, NO5, CA	1 (best 0.57)
6TNK	Carboxypeptidase T with N-sulfamoyl-L-valine	x-ray diffraction	A	ZN, NO5, CA	—
6Z28	Carboxypeptidase T mutant L254N with N-sulfamoyl-L-glutamic acid	x-ray diffraction	A	ZN, CA, SO4	—
6Z28	Carboxypeptidase T mutant L254N with N-sulfamoyl-L-glutamic acid	x-ray diffraction	A	ZN, CA, SO4	—
7AQP	T262S, A251S, L254S, L211Q mutant of carboxypeptidase T from thermoactinomyces vulgaris	x-ray diffraction	A	ZN, CA, SO4	—
7ARU	L254N mutant of carboxypeptidase T from thermoactinomyces vulgaris N- sulfamoyl-L-valine	x-ray diffraction	A	ZN, NO5, CA	—
7Q87	Carboxypeptidase T with (S)-3-phenyllactic acid	x-ray diffraction	A	ZN, HFA, CA, SO4	—
8QVO	L211Q, L254N, T262G mutant of carboxypeptidase T from Thermoactinomyces vulgaris	x-ray diffraction	A	ZN, SO4, CA	2 (best 0.56)
P29068	AlphaFold monomer V2.0 prediction for carboxypeptidase T (P29068)	predicted	A	—	—

Ligands

CA · Calcium ion · in 21 records
ZN · Zinc ion · in 21 records
SO4 · Sulfate ion · in 14 records
0X9 · N~2~-sulfamoyl-L-arginine · in 4 records
LU0 · Sulphamoil Leucine · in 4 records
NO5 · (2~{S})-3-methyl-2-(sulfamoylamino)butanoic acid · in 3 records
7B0 · (2~{S})-6-azanyl-2-(sulfamoylamino)hexanoic acid · in 2 records
3K0 · N-sulfamoyl-L-glutamic acid · in 1 record
HFA · Alpha-hydroxy-beta-phenyl-propionic acid · in 1 record

Experiment against prediction

7Q87 chain A against the predicted model P29068: TM-score 1.00, RMSD 0.48 Å
6TNK chain A against the predicted model P29068: TM-score 1.00, RMSD 0.49 Å
6TNK chain A against the predicted model P29068: TM-score 1.00, RMSD 0.49 Å
4DJL chain A against the predicted model P29068: TM-score 1.00, RMSD 0.49 Å
4DJL chain A against the predicted model P29068: TM-score 1.00, RMSD 0.49 Å
4DUK chain A against the predicted model P29068: TM-score 1.00, RMSD 0.49 Å
4DUK chain A against the predicted model P29068: TM-score 1.00, RMSD 0.49 Å
6T9Y chain A against the predicted model P29068: TM-score 1.00, RMSD 0.49 Å
6T9Y chain A against the predicted model P29068: TM-score 1.00, RMSD 0.49 Å
4GM5 chain A against the predicted model P29068: TM-score 1.00, RMSD 0.49 Å

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.