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Ligand · HFA

HFA · Alpha-hydroxy-beta-phenyl-propionic acid

HFA, Alpha-hydroxy-beta-phenyl-propionic acid (C9 H10 O3, 166.2 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
HFA
Formula
C9 H10 O3
Class
ligand
Structures
3
PDB entries
3

Binding sites

HFA in 3 structures; the first of them:

  • 6A0G · The crystal structure of mandelate oxidase mutant Y128F with B- phenyllactate · HFA A402 · binds PHE24, TYR80, LEU108, MET160, ARG163, HIS252, ARG255
  • 6ZUP · Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6… · HFA B405 · binds ILE13, LEU14, ILE33, GLY34, TRP130, ASN183, PHE348, ARG374 and 1 more
  • 7Q87 · Carboxypeptidase T with (S)-3-phenyllactic acid · HFA A402 · binds HIS69, ARG129, ASN146, ARG147, LEU211, ALA251, LEU254, TYR255 and 4 more

Residues it binds most

ARG 6, LEU 5, ILE 3, TYR 4, GLU 3, HIS 3, ASN 3, PHE 3, THR 2, ALA 2 (residue and the binding sites it lines).

Found with

  • FMN · Flavin mononucleotide
  • PLP · Pyridoxal-5'-phosphate
  • CA · Calcium ion
  • MG · Magnesium ion
  • ZN · Zinc ion
  • NO3 · Nitrate ion
  • SO4 · Sulfate ion

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