UniProt P28566
5-hydroxytryptamine receptor 1E (P28566)
5-hydroxytryptamine receptor 1E (UniProt P28566): 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P28566
- Protein
- 5-hydroxytryptamine receptor 1E
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 5 · 1 record with a druggable one
Structures
3 records of P28566 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7E33 | Serotonin 1E (5-HT1E) receptor-gi protein complex | electron microscopy | R | HVU | — |
| 8UH3 | Serotonin 1E receptor (5-HT1eR)-Gi1 Complex bound with Setiptiline | electron microscopy | D | CLR, WOQ | 5 (best 0.79) |
| P28566 | AlphaFold monomer V2.0 prediction for 5-hydroxytryptamine receptor 1E (P28566) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8UH3 chain D against the predicted model P28566: TM-score 0.94, RMSD 1.71 Å
- 7E33 chain R against the predicted model P28566: TM-score 0.93, RMSD 1.88 Å
- 7E33 chain R against the predicted model P0ABE7: TM-score 0.29, RMSD 4.37 Å
Elsewhere
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