UniProt P25874
Mitochondrial brown fat uncoupling protein 1 (P25874)
Mitochondrial brown fat uncoupling protein 1 (UniProt P25874): 4 experimental structures on GenesisL1, 5 ligands bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P25874
- Protein
- Mitochondrial brown fat uncoupling protein 1
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 9 · 3 records with a druggable one
Structures
4 records of P25874 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8G8W | Molecular mechanism of nucleotide inhibition of human uncoupling protein 1 | electron microscopy | A | GTP, CDL | 5 (best 0.80) |
| 8HBW | Structure of human UCP1 in the ATP-bound state | electron microscopy | A | ATP, CDL, PC1 | 2 (best 0.80) |
| 8J1N | Structure of human UCP1 in the DNP-bound state | electron microscopy | A | DNF, CDL, PC1 | 2 (best 0.79) |
| P25874 | AlphaFold monomer V2.0 prediction for mitochondrial brown fat uncoupling protein 1 (P25874) | — | — | — |
Ligands
Elsewhere
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