UniProt P24733
Myosin heavy chain, striated muscle (P24733)
Myosin heavy chain, striated muscle (UniProt P24733): 40 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P24733
- Protein
- Myosin heavy chain, striated muscle
- Experimental structures
- 40
- Predicted models
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
41 records of P24733 in the MolNFT archive: 40 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B7T | Myosin digested by papain | x-ray diffraction | A | — | — |
| 1B7T | Myosin digested by papain | x-ray diffraction | A | — | — |
| 1DFK | Nucleotide-free scallop myosin S1-near rigor state | x-ray diffraction | A | — | — |
| 1DFK | Nucleotide-free scallop myosin S1-near rigor state | x-ray diffraction | A | — | — |
| 1DFL | Scallop myosin S1 complexed with MGADP:VANADATE-transition state | x-ray diffraction | A, B | — | — |
| 1DFL | Scallop myosin S1 complexed with MGADP:VANADATE-transition state | x-ray diffraction | A, B | — | — |
| 1KK7 | Scallop myosin in the near rigor conformation | x-ray diffraction | A | — | — |
| 1KK7 | Scallop myosin in the near rigor conformation | x-ray diffraction | A | — | — |
| 1KK8 | SCALLOP MYOSIN (S1-ADP-BeFx) IN THE ACTIN-DETACHED CONFORMATION | x-ray diffraction | A | — | — |
| 1KK8 | Scallop myosin (S1-ADP-befx) in the actin-detached conformation | x-ray diffraction | A | — | — |
| 1KQM | Scallop myosin S1-amppnp in the actin-detached conformation | x-ray diffraction | A | — | — |
| 1KQM | Scallop myosin S1-amppnp in the actin-detached conformation | x-ray diffraction | A | — | — |
| 1KWO | SCALLOP MYOSIN S1-ATPgammaS-p-PDM IN THE ACTIN-DETACHED CONFORMATION | x-ray diffraction | A | — | — |
| 1KWO | Scallop myosin S1-atpgammas-P-pdm in the actin-detached conformation | x-ray diffraction | A | — | — |
| 1L2O | SCALLOP MYOSIN S1-ADP-p-PDM IN THE ACTIN-DETACHED CONFORMATION | x-ray diffraction | A | — | — |
| 1L2O | Scallop myosin S1-ADP-P-pdm in the actin-detached conformation | x-ray diffraction | A | — | — |
| 1QVI | Crystal structure of scallop myosin S1 in the pre-power stroke state to 2.6 Angstrom resolution… | x-ray diffraction | A | — | — |
| 1QVI | Crystal structure of scallop myosin S1 in the pre-power stroke state to 2.6 ångström resolution… | x-ray diffraction | A | — | — |
| 1S5G | Structure of Scallop myosin S1 reveals a novel nucleotide conformation | x-ray diffraction | A | — | — |
| 1S5G | Structure of scallop myosin S1 reveals a novel nucleotide conformation | x-ray diffraction | A | — | — |
| 1SCM | Structure of the regulatory domain of scallop myosin at 2.8 ångströms resolution | x-ray diffraction | A | — | — |
| 1SCM | Structure of the regulatory domain of scallop myosin at 2.8 ångströms resolution | x-ray diffraction | A | — | — |
| 1SR6 | Structure of nucleotide-free scallop myosin S1 | x-ray diffraction | A | — | — |
| 1SR6 | Structure of nucleotide-free scallop myosin S1 | x-ray diffraction | A | — | — |
| 1WDC | Scallop myosin regulatory domain | x-ray diffraction | A | — | — |
| 1WDC | Scallop myosin regulatory domain | x-ray diffraction | A | — | — |
| 2W4T | Isometrically contracting insect asynchronous flight muscle | electron microscopy | C | — | — |
| 2W4T | Isometrically contracting insect asynchronous flight muscle | electron microscopy | C | — | — |
| 2W4V | Isometrically contracting insect asynchronous flight muscle quick frozen after a quick release step | electron microscopy | C | — | — |
| 2W4V | Isometrically contracting insect asynchronous flight muscle quick frozen after a quick release step | electron microscopy | C | — | — |
| 2W4W | Isometrically contracting insect asynchronous flight muscle quick frozen after a quick stretch step | electron microscopy | C | — | — |
| 2W4W | Isometrically contracting insect asynchronous flight muscle quick frozen after a quick stretch step | electron microscopy | C | — | — |
| 3BAS | Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (C2) form | x-ray diffraction | A, B | — | — |
| 3BAS | Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (C2) form | x-ray diffraction | A, B | — | — |
| 3BAT | Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (P21) form | x-ray diffraction | A, B, C, D | — | — |
| 3BAT | Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (P21) form | x-ray diffraction | A, B, C, D | — | — |
| 3JTD | Calcium-free Scallop Myosin Regulatory Domain with ELC-D19A Point Mutation | x-ray diffraction | A | — | — |
| 3JTD | Calcium-free scallop myosin regulatory domain with elc-D19A point mutation | x-ray diffraction | A | — | — |
| 3JVT | Calcium-bound Scallop Myosin Regulatory Domain (Lever Arm) with Reconstituted Complete Light Chains | x-ray diffraction | A | — | — |
| 3JVT | Calcium-bound scallop myosin regulatory domain (lever arm) with reconstituted complete light chains | x-ray diffraction | A | — | — |
| P24733 | AlphaFold monomer V2.0 prediction for myosin heavy chain, striated muscle (P24733) | predicted | A | — | 8 (best 0.76) |
Experiment against prediction
- 1DFL chain A against the predicted model P24733: TM-score 0.94, RMSD 2.44 Å
- 1DFL chain A against the predicted model P24733: TM-score 0.94, RMSD 2.44 Å
- 1QVI chain A against the predicted model P24733: TM-score 0.93, RMSD 2.39 Å
- 1QVI chain A against the predicted model P24733: TM-score 0.93, RMSD 2.39 Å
- 1DFL chain B against the predicted model P24733: TM-score 0.93, RMSD 2.39 Å
- 1DFL chain B against the predicted model P24733: TM-score 0.93, RMSD 2.39 Å
- 2W4T chain C against the predicted model P24733: TM-score 0.89, RMSD 2.82 Å
- 2W4T chain C against the predicted model P24733: TM-score 0.89, RMSD 2.82 Å
- 2W4W chain C against the predicted model P24733: TM-score 0.88, RMSD 2.99 Å
- 2W4W chain C against the predicted model P24733: TM-score 0.88, RMSD 2.99 Å
Elsewhere
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