UniProt P24666
Low molecular weight phosphotyrosine protein phosphatase (P24666)
Low molecular weight phosphotyrosine protein phosphatase (UniProt P24666), EC 3.1.3.2, 3.1.3.48: 31 experimental structures on GenesisL1, 5 ligands bound, 5 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P24666
- Protein
- Low molecular weight phosphotyrosine protein phosphatase
- EC
- 3.1.3.2, 3.1.3.48
- Experimental structures
- 31
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 5 · 0 records with a druggable one
Structures
31 records of P24666 in the MolNFT archive: 31 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1XWW | Crystal Structure of Human B-form Low Molecular Weight Phosphotyrosyl Phosphatase at 1.6 Angstrom… | x-ray diffraction | A | — | — |
| 1XWW | Crystal structure of human B-form low molecular weight phosphotyrosyl phosphatase at 1.6 ångström… | x-ray diffraction | A | — | — |
| 3N8I | Crystal structure of the A isoform of human cytoplasmic protein tyrosine phosphatase (HCPTP-A) in… | x-ray diffraction | A | — | — |
| 3N8I | Crystal structure of the a isoform of human cytoplasmic protein tyrosine phosphatase (hcptp-a) in… | x-ray diffraction | A | — | — |
| 4Z99 | Crystal structure of the apo Low Molecular Weight Protein Tyrosine Phosphatase isoform A | x-ray diffraction | A | — | — |
| 4Z99 | Crystal structure of the apo low molecular weight protein tyrosine phosphatase isoform a | x-ray diffraction | A | — | — |
| 4Z9A | Crystal structure of Low Molecular Weight Protein Tyrosine Phosphatase isoform A complexed with… | x-ray diffraction | A | — | — |
| 4Z9A | Crystal structure of low molecular weight protein tyrosine phosphatase isoform a complexed with… | x-ray diffraction | A | — | — |
| 4Z9B | Crystal structure of Low Molecular Weight Protein Tyrosine Phosphatase isoform A complexed with… | x-ray diffraction | A | — | — |
| 4Z9B | Crystal structure of low molecular weight protein tyrosine phosphatase isoform a complexed with… | x-ray diffraction | A | — | — |
| 5JNR | Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A | x-ray diffraction | A | — | 1 (best 0.37) |
| 5JNR | Crystal structure of human low molecular weight protein tyrosine phosphatase (lmptp) type a | x-ray diffraction | A | — | — |
| 5JNS | Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A… | x-ray diffraction | A | PO4 | 1 (best 0.35) |
| 5JNS | Crystal structure of human low molecular weight protein tyrosine phosphatase (lmptp) type a… | x-ray diffraction | A | — | — |
| 5JNT | Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A… | x-ray diffraction | A | — | — |
| 5JNT | Crystal structure of human low molecular weight protein tyrosine phosphatase (lmptp) type a… | x-ray diffraction | A | — | — |
| 5KQG | Co-crystal structure of LMW-PTP in complex with 2-(benzothiazol-2-ylamino)-2-oxo-1-phenylethanesulfo… | x-ray diffraction | A | 6VX | 1 (best 0.47) |
| 5KQG | Co-crystal structure of lmw-ptp in complex with 2-(benzothiazol-2… | x-ray diffraction | A | 6VX | — |
| 5KQL | Co-crystal structure of LMW-PTP in complex with 2-oxo-1-phenyl-2-(phenylamino)ethanesulfonic acid | x-ray diffraction | A | 6VY | 1 (best 0.48) |
| 5KQL | Co-crystal structure of lmw-ptp in complex with 2-oxo-1-phenyl-2- (PHENYLAMINO)ETHANESULFONIC acid | x-ray diffraction | A | 6VY | — |
| 5KQM | Co-crystal structure of LMW-PTP in complex with MES | x-ray diffraction | A | — | — |
| 5KQM | Co-crystal structure of lmw-ptp in complex with mes | x-ray diffraction | A | — | — |
| 5KQP | Crystal structure of Apo-form LMW-PTP | x-ray diffraction | A | — | — |
| 5KQP | Crystal structure of apo-form lmw-ptp | x-ray diffraction | A | — | — |
| 5PNT | Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. implications for… | x-ray diffraction | A | — | — |
| 5PNT | Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. implications for… | x-ray diffraction | A | — | — |
| 6Y2V | Crystal structure of the double mutant L13R I16K of low molecular weight protein tyrosine… | x-ray diffraction | A | PO4 | — |
| 6Y2W | Crystal structure of the single mutant I16K of Low Molecular Weight Protein Tyrosine Phosphatase… | x-ray diffraction | A | — | 1 (best 0.36) |
| 6Y2W | Crystal structure of the single mutant I16K of low molecular weight protein tyrosine phosphatase… | x-ray diffraction | A | — | — |
| 7KH8 | Human lmptp in complex with inhibitor | x-ray diffraction | A, B | WE7, NO3 | — |
| P24666 | AlphaFold monomer V2.0 prediction for low molecular weight phosphotyrosine protein phosphatase… | — | — | — |
Ligands
- 6VX · (1~{S})-2-(1,3-benzothiazol-2-ylamino)-2-oxidanylidene-1-phenyl-ethanesulfonic acid · in 2 records
- 6VY · (1~{S})-2-oxidanylidene-1-phenyl-2-phenylazanyl-ethanesulfonic acid · in 2 records
- PO4 · Phosphate ion · in 2 records
- NO3 · Nitrate ion · in 1 record
- WE7 · 3-[(2,6-dichlorophenyl)methyl]-8-(2-methylphenyl)-3H-purin-6-amine · in 1 record
Elsewhere
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