MolNFT v1 · #112048 · protein
Crystal structure of the apo low molecular weight protein tyrosine phosphatase isoform a
4Z99 · Low molecular weight phosphotyrosine protein phosphatase: “Crystal structure of the apo low molecular weight protein tyrosine phosphatase isoform a”. X-ray diffraction, 1 pocket (best druggability 0.37). MolNFT v1 #112048 on…
- PDB
- 4Z99
- Type
- protein
- Length
- 164 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Low molecular weight phosphotyrosine protein phosphatase
- EC
- 3.1.3.48, 3.1.3.2
- UniProt
- P24666
- Pockets
- 1 · best druggability 0.37
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Low molecular weight phosphotyrosine protein phosphatase (EC 3.1.3.48, 3.1.3.2) | protein | 164 | 41% helix, 14% strand | P24666 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 54 | 0.37 | 0.79 | 12 | empty |
Compared structures
- 4Z99 · Crystal structure of the apo Low Molecular Weight Protein Tyrosine Phosphatase isoform A · the same entry in another collection · chain A against A, TM-score 1.00
- P24666 · AlphaFold monomer V2.0 prediction for low molecular weight phosphotyrosine protein… · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24666
- Elsewhere: RCSB PDB 4Z99 · PDBe 4Z99 · UniProt P24666
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