UniProt P23469
Receptor-type tyrosine-protein phosphatase epsilon (P23469)
Receptor-type tyrosine-protein phosphatase epsilon (UniProt P23469), EC 3.1.3.48: 7 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P23469
- Protein
- Receptor-type tyrosine-protein phosphatase epsilon
- EC
- 3.1.3.48
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 12 · 1 record with a druggable one
Structures
8 records of P23469 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2JJD | Protein Tyrosine Phosphatase, Receptor Type, E isoform | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2JJD | Protein tyrosine phosphatase, receptor type, E isoform | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6D3F | Crystal structure of the ptp epsilon D2 domain | x-ray diffraction | A, B | — | — |
| 6D4D | Crystal structure of the PTP epsilon D1 domain | x-ray diffraction | A, B | — | — |
| 6D4D | Crystal structure of the ptp epsilon D1 domain | x-ray diffraction | A, B | — | — |
| 6D4F | Crystal structure of PTP epsilon D2 domain (A455N/V457Y/E597D) | x-ray diffraction | A | — | 3 (best 0.50) |
| 6D4F | Crystal structure of ptp epsilon D2 domain (A455N/V457Y/E597D) | x-ray diffraction | A | — | — |
| P23469 | AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase epsilon (P23469) | predicted | A | — | 9 (best 0.79) |
Experiment against prediction
- 6D4D chain A against the predicted model P23469: TM-score 1.00, RMSD 0.41 Å
- 6D4D chain A against the predicted model P23469: TM-score 1.00, RMSD 0.41 Å
- 6D4D chain B against the predicted model P23469: TM-score 0.99, RMSD 0.44 Å
- 6D4D chain B against the predicted model P23469: TM-score 0.99, RMSD 0.44 Å
- 2JJD chain B against the predicted model P23469: TM-score 0.99, RMSD 0.75 Å
- 2JJD chain B against the predicted model P23469: TM-score 0.99, RMSD 0.75 Å
- 2JJD chain A against the predicted model P23469: TM-score 0.98, RMSD 1.02 Å
- 2JJD chain A against the predicted model P23469: TM-score 0.98, RMSD 1.02 Å
- 6D3F chain B against the predicted model P23469: TM-score 0.98, RMSD 0.76 Å
- 6D4F chain A against the predicted model P23469: TM-score 0.98, RMSD 0.80 Å
Elsewhere
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