UniProt P22888
Lutropin-choriogonadotropic hormone receptor (P22888)
Lutropin-choriogonadotropic hormone receptor (UniProt P22888): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P22888
- Protein
- Lutropin-choriogonadotropic hormone receptor
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 36 · 5 records with a druggable one
Structures
9 records of P22888 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7FIG | luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs complex | electron microscopy | R | NAG | 8 (best 0.80) |
| 7FIG | Luteinizing HORMONE/CHORIOGONADOTROPIN RECEPTOR(S277I)-chorionic gonadotropin-gs complex | electron microscopy | R | NAG | — |
| 7FIH | luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs-Org43553 complex | electron microscopy | R | 55Z | 12 (best 0.84) |
| 7FIH | Luteinizing HORMONE/CHORIOGONADOTROPIN RECEPTOR(S277I)-chorionic gonadotropin-gs-ORG43553 complex | electron microscopy | R | 55Z | — |
| 7FII | luteinizing hormone/choriogonadotropin receptor-chorionic gonadotropin-Gs complex | electron microscopy | R | — | 6 (best 0.86) |
| 7FII | Luteinizing HORMONE/CHORIOGONADOTROPIN receptor-chorionic gonadotropin-gs complex | electron microscopy | R | — | — |
| 7FIJ | luteinizing hormone/choriogonadotropin receptor | electron microscopy | R | — | 3 (best 0.88) |
| 7FIJ | Luteinizing HORMONE/CHORIOGONADOTROPIN receptor | electron microscopy | R | — | — |
| P22888 | AlphaFold monomer V2.0 prediction for lutropin-choriogonadotropic hormone receptor (P22888) | predicted | A | — | 7 (best 0.79) |
Ligands
Experiment against prediction
- 7FIH chain R against the predicted model P22888: TM-score 0.94, RMSD 2.32 Å
- 7FIH chain R against the predicted model P22888: TM-score 0.94, RMSD 2.32 Å
- 7FII chain R against the predicted model P22888: TM-score 0.91, RMSD 2.75 Å
- 7FII chain R against the predicted model P22888: TM-score 0.91, RMSD 2.75 Å
- 7FIG chain R against the predicted model P22888: TM-score 0.91, RMSD 2.92 Å
- 7FIG chain R against the predicted model P22888: TM-score 0.91, RMSD 2.92 Å
- 7FIJ chain R against the predicted model P22888: TM-score 0.72, RMSD 5.26 Å
- 7FIJ chain R against the predicted model P22888: TM-score 0.72, RMSD 5.26 Å
Elsewhere
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