UniProt P21866
KDP operon transcriptional regulatory protein KdpE (P21866)
KDP operon transcriptional regulatory protein KdpE (UniProt P21866): 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P21866
- Protein
- KDP operon transcriptional regulatory protein KdpE
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 28 · 7 records with a druggable one
Structures
13 records of P21866 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZH2 | Crystal Structure Of The Calcium-Bound Receiver Domain Of Kdp Potassium Transport System Response… | x-ray diffraction | A, B | CA | 2 (best 0.72) |
| 1ZH2 | Crystal structure of the calcium-bound receiver domain of kdp potassium transport system response… | x-ray diffraction | A, B | CA | 2 (best 0.72) |
| 1ZH4 | Crystal Structure Of The Mg+2/BeF3-Bound Receiver Domain Of Kdp Potassium Transport System Response… | x-ray diffraction | A, B | MG, BEF | 2 (best 0.73) |
| 1ZH4 | Crystal structure of the MG+2/BEF3-bound receiver domain of kdp potassium transport system response… | x-ray diffraction | A, B | MG, BEF | 2 (best 0.73) |
| 3ZQ7 | The Structure of DNA-binding domain of response regulator from Escherichia coli K-12 | x-ray diffraction | A | — | — |
| 3ZQ7 | The structure of DNA-binding domain of response regulator from escherichia COLI K-12 | x-ray diffraction | A | — | — |
| 4KFC | Crystal structure of a hyperactive mutant of response regulator KdpE complexed to its promoter DNA | x-ray diffraction | A, B | — | 9 (best 0.53) |
| 4KFC | Crystal structure of a hyperactive mutant of response regulator kdpe complexed to its promoter DNA | x-ray diffraction | A, B | — | — |
| 4KNY | Crystal structure of the response regulator KdpE complexed to DNA in an active-like conformation | x-ray diffraction | A, B | — | 6 (best 0.54) |
| 4KNY | Crystal structure of the response regulator kdpe complexed to DNA in an active-like conformation | x-ray diffraction | A, B | — | — |
| 4L85 | Crystal structure of receiver domain of KdpE D52A mutant from E. coli | x-ray diffraction | A, B, C | IOD | 3 (best 0.62) |
| 4L85 | Crystal structure of receiver domain of kdpe D52A mutant from E. COLI | x-ray diffraction | A, B, C | — | — |
| P21866 | AlphaFold monomer V2.0 prediction for kdp operon transcriptional regulatory protein kdpe (P21866) | predicted | A | — | 2 (best 0.38) |
Ligands
Experiment against prediction
- 1ZH2 chain B against the predicted model P21866: TM-score 0.99, RMSD 0.48 Å
- 1ZH2 chain B against the predicted model P21866: TM-score 0.99, RMSD 0.48 Å
- 1ZH2 chain A against the predicted model P21866: TM-score 0.99, RMSD 0.50 Å
- 1ZH2 chain A against the predicted model P21866: TM-score 0.99, RMSD 0.50 Å
- 1ZH4 chain B against the predicted model P21866: TM-score 0.99, RMSD 0.49 Å
- 1ZH4 chain B against the predicted model P21866: TM-score 0.99, RMSD 0.49 Å
- 1ZH4 chain A against the predicted model P21866: TM-score 0.98, RMSD 0.60 Å
- 1ZH4 chain A against the predicted model P21866: TM-score 0.98, RMSD 0.60 Å
- 3ZQ7 chain A against the predicted model P21866: TM-score 0.96, RMSD 0.82 Å
- 3ZQ7 chain A against the predicted model P21866: TM-score 0.96, RMSD 0.82 Å
Elsewhere
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