UniProt P20051
Dihydroorotase (P20051)
Dihydroorotase (UniProt P20051), EC 3.5.2.3: 16 experimental structures on GenesisL1, 6 ligands bound, 75 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P20051
- Protein
- Dihydroorotase
- EC
- 3.5.2.3
- Experimental structures
- 16
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 75 · 4 records with a druggable one
Structures
16 records of P20051 in the MolNFT archive: 16 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6L0A | Crystal structure of dihydroorotase in complex with malate at pH7 from Saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | ZN, LMR | 20 (best 0.79) |
| 6L0A | Crystal structure of dihydroorotase in complex with malate at PH7 from saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | ZN, LMR | — |
| 6L0B | Crystal structure of dihydroorotase in complex with fluorouracil from saccharomyces cerevisiae | x-ray diffraction | A, C, B, D | ZN, URF | — |
| 6L0F | Crystal structure of dihydroorotase in complex with 5-aminouracil from saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | WBU, ZN | — |
| 6L0G | Crystal structure of dihydroorotase in complex with malate at pH6 from Saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | ZN, LMR | 16 (best 0.81) |
| 6L0G | Crystal structure of dihydroorotase in complex with malate at PH6 from saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | ZN, LMR | — |
| 6L0H | Crystal structure of dihydroorotase in complex with malate at PH7 from saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | ZN, LMR | — |
| 6L0I | Crystal structure of dihydroorotase in complex with malate at pH6.5 from Saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | ZN, LMR | 20 (best 0.78) |
| 6L0I | Crystal structure of dihydroorotase in complex with malate at PH6.5 from saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | ZN, LMR | — |
| 6L0J | Crystal structure of dihydroorotase in complex with malate at PH7.5 from saccharomyces cerevisiae | x-ray diffraction | A, D, B, C | ZN, LMR | — |
| 6L0K | Crystal structure of dihydroorotase in complex with malate at pH9 from Saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | ZN, LMR | 19 (best 0.78) |
| 6L0K | Crystal structure of dihydroorotase in complex with malate at PH9 from saccharomyces cerevisiae | x-ray diffraction | A, B, C, D | ZN, LMR | — |
| 7CA0 | Crystal structure of dihydroorotase in complex with 5-fluoroorotic acid from Saccharomyces… | x-ray diffraction | A, B, C, D | ZN, FOT | — |
| 7CA0 | Crystal structure of dihydroorotase in complex with 5-fluoroorotic acid from saccharomyces… | x-ray diffraction | A, B, C, D | ZN, FOT | — |
| 7CA1 | Crystal structure of dihydroorotase in complex with plumbagin from saccharomyces cerevisiae | x-ray diffraction | A, C, B, D | LMR, ZN, 90R | — |
| P20051 | AlphaFold monomer V2.0 prediction for dihydroorotase (P20051) | — | — | — |
Ligands
- ZN · Zinc ion · in 15 records
- LMR · (2S)-2-hydroxybutanedioic acid · in 11 records
- FOT · 5-fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid · in 2 records
- 90R · 5-hydroxy-2-methylnaphthalene-1,4-dione · in 1 record
- URF · 5-fluorouracil · in 1 record
- WBU · 5-amino-1H-pyrimidine-2,4-dione · in 1 record
Elsewhere
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