UniProt P20035
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (P20035)
Hypoxanthine-guanine-xanthine phosphoribosyltransferase (UniProt P20035): 8 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P20035
- Protein
- Hypoxanthine-guanine-xanthine phosphoribosyltransferase
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
9 records of P20035 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CJB | Malarial purine phosphoribosyltransferase | x-ray diffraction | A, B, C, D | — | — |
| 1CJB | Malarial purine phosphoribosyltransferase | x-ray diffraction | A, B, C, D | — | — |
| 2VFA | Crystal structure of a chimera of Plasmodium falciparum and human hypoxanthine-guanine… | x-ray diffraction | A, B | — | — |
| 2VFA | Crystal structure of a chimera of plasmodium falciparum and human hypoxanthine-guanine… | x-ray diffraction | A, B | — | — |
| 3OZF | Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase… | x-ray diffraction | A, B, C, D | — | — |
| 3OZF | Crystal structure of plasmodium falciparum hypoxanthine-guanine- xanthine phosphoribosyltransferase… | x-ray diffraction | A, B, C, D | — | — |
| 3OZG | Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase… | x-ray diffraction | A, B, C, D | — | — |
| 3OZG | Crystal structure of plasmodium falciparum hypoxanthine-guanine- xanthine phosphoribosyltransferase… | x-ray diffraction | A, B, C, D | — | — |
| P20035 | AlphaFold monomer V2.0 prediction for hypoxanthine-guanine-xanthine phosphoribosyltransferase… | predicted | A | — | 2 (best 0.75) |
Experiment against prediction
- 3OZF chain C against the predicted model P20035: TM-score 0.99, RMSD 0.78 Å
- 3OZF chain C against the predicted model P20035: TM-score 0.99, RMSD 0.78 Å
- 1CJB chain A against the predicted model P20035: TM-score 0.98, RMSD 0.80 Å
- 1CJB chain A against the predicted model P20035: TM-score 0.98, RMSD 0.80 Å
- 3OZG chain A against the predicted model P20035: TM-score 0.98, RMSD 0.81 Å
- 3OZG chain A against the predicted model P20035: TM-score 0.98, RMSD 0.81 Å
- 3OZG chain B against the predicted model P20035: TM-score 0.98, RMSD 0.86 Å
- 3OZG chain B against the predicted model P20035: TM-score 0.98, RMSD 0.86 Å
- 3OZG chain C against the predicted model P20035: TM-score 0.98, RMSD 0.86 Å
- 3OZG chain C against the predicted model P20035: TM-score 0.98, RMSD 0.86 Å
Elsewhere
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