UniProt P19803
Rho GDP-dissociation inhibitor 1 (P19803)
Rho GDP-dissociation inhibitor 1 (UniProt P19803): 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P19803
- Protein
- Rho GDP-dissociation inhibitor 1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 3 · 1 record with a druggable one
Structures
11 records of P19803 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AJW | Structure of rhogdi: a C-terminal binding domain targets an N-terminal inhibitory peptide to… | solution nmr | A | — | — |
| 1AJW | Structure of rhogdi: a C-terminal binding domain targets an N-terminal inhibitory peptide to… | solution nmr | A | — | — |
| 1DOA | Structure of the rho family gtp-binding protein cdc42 in complex with the multifunctional regulator… | x-ray diffraction | B | — | — |
| 1DOA | Structure of the rho family GTP-binding protein CDC42 in complex with the multifunctional regulator… | x-ray diffraction | B | — | — |
| 1GDF | Structure of rhogdi: a C-terminal binding domain targets an N-terminal inhibitory peptide to… | solution nmr | A | — | — |
| 1GDF | Structure of rhogdi: a C-terminal binding domain targets an N-terminal inhibitory peptide to… | solution nmr | A | — | — |
| 5FR1 | Double acetylated RhoGDI-alpha in complex with RhoA-GDP | x-ray diffraction | B | MG | — |
| 5FR1 | Double acetylated rhogdi-alpha in complex with rhoa-GDP | x-ray diffraction | B | — | — |
| 5FR2 | Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178 | x-ray diffraction | B | FAR, BGC | 3 (best 0.79) |
| 5FR2 | Farnesylated rhoa-GDP in complex with rhogdi-alpha, lysine acetylated at K178 | x-ray diffraction | B | — | — |
| P19803 | AlphaFold monomer V2.0 prediction for rho GDP-dissociation inhibitor 1 (P19803) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5FR2 chain B against the predicted model P19803: TM-score 0.96, RMSD 1.16 Å
- 5FR2 chain B against the predicted model P19803: TM-score 0.96, RMSD 1.16 Å
- 1DOA chain B against the predicted model P19803: TM-score 0.96, RMSD 1.14 Å
- 1DOA chain B against the predicted model P19803: TM-score 0.96, RMSD 1.14 Å
- 5FR1 chain B against the predicted model P19803: TM-score 0.92, RMSD 1.56 Å
- 5FR1 chain B against the predicted model P19803: TM-score 0.92, RMSD 1.56 Å
- 1AJW chain A against the predicted model P19803: TM-score 0.91, RMSD 1.78 Å
- 1AJW chain A against the predicted model P19803: TM-score 0.91, RMSD 1.78 Å
- 1GDF chain A against the predicted model P19803: TM-score 0.89, RMSD 1.76 Å
- 1GDF chain A against the predicted model P19803: TM-score 0.89, RMSD 1.76 Å
Elsewhere
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