MolNFT v1 · #870 · protein

Structure of rhogdi: a C-terminal binding domain targets an N-terminal inhibitory peptide to gtpases, NMR, 20 structures

1AJW: “Structure of rhogdi: a C-terminal binding domain targets an N-terminal inhibitory peptide to gtpases, NMR, 20…”. Solution nmr, 1 pocket (best druggability 0.48). MolNFT v1 #870 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 1AJW
Type: protein
Length: 145 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Rhogdi
UniProt: P19803
Pockets: 1 · best druggability 0.48

Structure

solution nmr · 1 distinct chain · 0% helix, 52% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rhogdi	protein	145	0% helix, 52% strand	P19803

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	97	0.48	0.80	20	empty

Compared structures

1AJW · Structure of rhogdi: a C-terminal binding domain targets an N-terminal inhibitory peptide… · the same entry in another collection · chain A against A, TM-score 1.00
P19803 · AlphaFold monomer V2.0 prediction for rho GDP-dissociation inhibitor 1 (P19803) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19803
Elsewhere: RCSB PDB 1AJW · PDBe 1AJW · UniProt P19803

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