UniProt P19484
Transcription factor EB (P19484)
Transcription factor EB (UniProt P19484): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P19484
- Protein
- Transcription factor EB
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 2 records with a druggable one
Structures
4 records of P19484 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UXC | cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex with symmetry expansion | electron microscopy | R | GTP, GDP | 3 (best 0.82) |
| 7UXH | cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex | electron microscopy | T, j | GDP, GTP | 3 (best 0.82) |
| 7Y62 | Crystal structure of human TFEB HLHLZ domain | x-ray diffraction | A, B | — | — |
| P19484 | AlphaFold monomer V2.0 prediction for transcription factor eb (P19484) | predicted | A | — | 1 (best 0.25) |
Ligands
Experiment against prediction
- 7Y62 chain B against the predicted model P19484: TM-score 0.84, RMSD 1.88 Å
- 7Y62 chain A against the predicted model P19484: TM-score 0.67, RMSD 2.71 Å
- 7UXH chain T against the predicted model P19484: TM-score 0.42, RMSD 2.76 Å
- 7UXH chain j against the predicted model P19484: TM-score 0.42, RMSD 3.22 Å
- 7UXC chain R against the predicted model P19484: TM-score 0.42, RMSD 3.21 Å
Elsewhere
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