UniProt P19174
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (P19174)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (UniProt P19174): 9 experimental structures and 1 predicted model on GenesisL1, 19 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P19174
- Protein
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 19 · 1 record with a druggable one
Structures
10 records of P19174 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HSQ | Solution structure of the SH3 domain of phospholipase cgamma | solution nmr | A | — | — |
| 1HSQ | Solution structure of the SH3 domain of phospholipase cgamma | solution nmr | A | — | — |
| 2HSP | Solution structure of the SH3 domain of phospholipase cgamma | solution nmr | A | — | — |
| 2HSP | Solution structure of the SH3 domain of phospholipase cgamma | solution nmr | A | — | — |
| 4EY0 | Structure of tandem SH2 domains from PLCgamma1 | x-ray diffraction | A, B, C, D | — | — |
| 4EY0 | Structure of tandem SH2 domains from PLCGAMMA1 | x-ray diffraction | A, B, C, D | — | — |
| 4FBN | Insights into structural integration of the PLCgamma regulatory region and mechanism of… | x-ray diffraction | A | — | — |
| 4FBN | Insights into structural integration of the plcgamma regulatory region and mechanism of… | x-ray diffraction | A | — | — |
| 7NXE | Structure of the phospholipase C gamma 1 TSH2 domain in complex with a phosphorylated kshv PK15… | x-ray diffraction | A | — | — |
| P19174 | AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase… | predicted | A | — | 19 (best 0.82) |
Experiment against prediction
- 7NXE chain A against the predicted model P19174: TM-score 0.95, RMSD 1.29 Å
- 4FBN chain A against the predicted model P19174: TM-score 0.94, RMSD 1.64 Å
- 4FBN chain A against the predicted model P19174: TM-score 0.94, RMSD 1.64 Å
- 4EY0 chain A against the predicted model P19174: TM-score 0.92, RMSD 1.94 Å
- 4EY0 chain A against the predicted model P19174: TM-score 0.92, RMSD 1.94 Å
- 2HSP chain A against the predicted model P19174: TM-score 0.71, RMSD 2.54 Å
- 2HSP chain A against the predicted model P19174: TM-score 0.71, RMSD 2.54 Å
- 1HSQ chain A against the predicted model P19174: TM-score 0.71, RMSD 2.68 Å
- 1HSQ chain A against the predicted model P19174: TM-score 0.71, RMSD 2.68 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.