UniProt P18357
Regulatory protein BlaR1 (P18357)
Regulatory protein BlaR1 (UniProt P18357): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P18357
- Protein
- Regulatory protein BlaR1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
11 records of P18357 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1XA1 | Crystal structure of the sensor domain of BlaR1 from Staphylococcus aureus in its apo form | x-ray diffraction | A, B, C, D | — | — |
| 1XA1 | Crystal structure of the sensor domain of BLAR1 from staphylococcus aureus in its apo form | x-ray diffraction | A, B, C, D | — | — |
| 1XA7 | Crystal structure of the benzylpenicillin-acylated BlaR1 sensor domain from Staphylococcus aureus | x-ray diffraction | A, B | — | — |
| 1XA7 | Crystal structure of the benzylpenicillin-acylated BLAR1 sensor domain from staphylococcus aureus | x-ray diffraction | A, B | — | — |
| 1XKZ | Crystal structure of the acylated beta-lactam sensor domain of Blar1 from S. aureus | x-ray diffraction | A, B, C, D | — | — |
| 1XKZ | Crystal structure of the acylated beta-lactam sensor domain of BLAR1 from S. aureus | x-ray diffraction | A, B, C, D | — | — |
| 3UY6 | BlaR1 sensor domain from Staphylococcus aureus with N439V mutation | x-ray diffraction | A, B | — | — |
| 3UY6 | BLAR1 sensor domain from staphylococcus aureus with N439V mutation | x-ray diffraction | A, B | — | — |
| 6O9W | Crystal structure of staphylococcus aureus BLAR1 antibiotic-sensor domain in complex with avibactam | x-ray diffraction | A, B | — | — |
| 8C0S | Crystal structure of S. aureus BlaR1 sensor domain in complex with an imidazole inhibitor | x-ray diffraction | A, B | SYU | 3 (best 0.77) |
| P18357 | AlphaFold monomer V2.0 prediction for regulatory protein BLAR1 (P18357) | predicted | A | — | — |
Ligands
- SYU · 3-[[2,4-bis(trifluoromethyl)phenyl]methyl]-5-(hydroxymethyl)-1~{H}-imidazole-2-thione · in 1 record
Experiment against prediction
- 1XKZ chain D against the predicted model P18357: TM-score 0.99, RMSD 0.53 Å
- 1XKZ chain D against the predicted model P18357: TM-score 0.99, RMSD 0.53 Å
- 1XKZ chain A against the predicted model P18357: TM-score 0.99, RMSD 0.63 Å
- 1XKZ chain A against the predicted model P18357: TM-score 0.99, RMSD 0.63 Å
- 1XKZ chain B against the predicted model P18357: TM-score 0.99, RMSD 0.66 Å
- 1XKZ chain B against the predicted model P18357: TM-score 0.99, RMSD 0.66 Å
- 1XA1 chain B against the predicted model P18357: TM-score 0.99, RMSD 0.65 Å
- 1XA1 chain B against the predicted model P18357: TM-score 0.99, RMSD 0.65 Å
- 1XKZ chain C against the predicted model P18357: TM-score 0.99, RMSD 0.67 Å
- 1XKZ chain C against the predicted model P18357: TM-score 0.99, RMSD 0.67 Å
Elsewhere
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