UniProt P17931
Galectin-3 (P17931)
Galectin-3 (UniProt P17931): 187 experimental structures on GenesisL1, 74 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P17931
- Protein
- Galectin-3
- Experimental structures
- 187
- Predicted models
- 0
- Ligands
- 74
- Pockets
- 21 · 2 records with a druggable one
Structures
187 records of P17931 in the MolNFT archive: 187 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A3K | X-ray crystal structure of the human galectin-3 carbohydrate recognition domain (crd) at 2.1… | x-ray diffraction | A | — | — |
| 1A3K | X-ray crystal structure of the human galectin-3 carbohydrate recognition domain (crd) at 2.1… | x-ray diffraction | A | — | — |
| 1KJL | High Resolution X-Ray Structure of Human Galectin-3 in complex with LacNAc | x-ray diffraction | A | — | — |
| 1KJL | High resolution X-ray structure of human galectin-3 in complex with lacnac | x-ray diffraction | A | — | — |
| 1KJR | Crystal Structure of the human galectin-3 CRD in complex with a 3'-derivative of N-Acetyllactosamine | x-ray diffraction | A | — | — |
| 1KJR | Crystal structure of the human galectin-3 crd in complex with a 3'- derivative of… | x-ray diffraction | A | — | — |
| 2NMN | Crystal structure of human galectin-3 carbohydrate-recognising domain at 2.45 angstrom resolution | x-ray diffraction | A | — | — |
| 2NMN | Crystal structure of human galectin-3 carbohydrate-recognising domain at 2.45 ångström resolution | x-ray diffraction | A | — | — |
| 2NMO | Crystal structure of human galectin-3 carbohydrate-recognition domain at 1.35 angstrom resolution | x-ray diffraction | A | — | — |
| 2NMO | Crystal structure of human galectin-3 carbohydrate-recognition domain at 1.35 ångström resolution | x-ray diffraction | A | — | — |
| 2NN8 | Crystal structure of human galectin-3 carbohydrate-recognition domain with lactose bound, at 1.35… | x-ray diffraction | A | — | — |
| 2NN8 | Crystal structure of human galectin-3 carbohydrate-recognition domain with lactose bound, at 1.35… | x-ray diffraction | A | — | — |
| 2XG3 | Human galectin-3 in complex with a benzamido-N-acetyllactoseamine inhibitor | x-ray diffraction | A | — | — |
| 2XG3 | Human galectin-3 in complex with a benzamido-N-acetyllactoseamine inhibitor | x-ray diffraction | A | — | — |
| 3AYA | Crystal structure of galectin-3 CRD domian complexed with Thomsen-Friedenreich antigen | x-ray diffraction | A, B | — | — |
| 3AYA | Crystal structure of galectin-3 crd domian complexed with thomsen- friedenreich antigen | x-ray diffraction | A, B | — | — |
| 3AYC | Crystal structure of galectin-3 CRD domian complexed with GM1 pentasaccharide | x-ray diffraction | A, B | — | — |
| 3AYC | Crystal structure of galectin-3 crd domian complexed with GM1 pentasaccharide | x-ray diffraction | A, B | — | — |
| 3AYD | Crystal structure of galectin-3 CRD domian complexed with TFN | x-ray diffraction | A | — | — |
| 3AYD | Crystal structure of galectin-3 crd domian complexed with tfn | x-ray diffraction | A | — | — |
| 3AYE | Crystal structure of galectin-3 CRD domian complexed with lactose | x-ray diffraction | A, B | — | — |
| 3AYE | Crystal structure of galectin-3 crd domian complexed with lactose | x-ray diffraction | A, B | — | — |
| 3T1L | Crystal structure of human Galectin-3 in complex with methyl… | x-ray diffraction | A | — | — |
| 3T1L | Crystal structure of human galectin-3 in complex with methyl 2-O… | x-ray diffraction | A | — | — |
| 3T1M | Crystal structure of human galectin-3 carbohydrate recognition domain in complex with methyl… | x-ray diffraction | A | — | — |
| 3T1M | Crystal structure of human galectin-3 carbohydrate recognition domain in complex with methyl… | x-ray diffraction | A | — | — |
| 3ZSJ | Crystal structure of Human Galectin-3 CRD in complex with Lactose at 0.86 angstrom resolution | x-ray diffraction | A | — | — |
| 3ZSJ | Crystal structure of human galectin-3 crd in complex with lactose at 0.86 ångström resolution | x-ray diffraction | A | — | — |
| 3ZSK | Crystal structure of Human Galectin-3 CRD with glycerol bound at 0.90 angstrom resolution | x-ray diffraction | A | — | — |
| 3ZSK | Crystal structure of human galectin-3 crd with glycerol bound at 0.90 ångström resolution | x-ray diffraction | A | — | — |
| 3ZSL | Crystal structure of Apo Human Galectin-3 CRD at 1.08 angstrom resolution, at cryogenic temperature | x-ray diffraction | A | — | — |
| 3ZSL | Crystal structure of apo human galectin-3 crd at 1.08 ångström resolution, at cryogenic temperature | x-ray diffraction | A | — | — |
| 3ZSM | Crystal structure of Apo Human Galectin-3 CRD at 1.25 angstrom resolution, at room temperature | x-ray diffraction | A | — | — |
| 3ZSM | Crystal structure of apo human galectin-3 crd at 1.25 ångström resolution, at room temperature | x-ray diffraction | A | — | — |
| 4BLI | Galectin-3c in complex with Bisamido-thiogalactoside derivate 1 | x-ray diffraction | A | — | — |
| 4BLI | Galectin-3C in complex with bisamido-thiogalactoside derivate 1 | x-ray diffraction | A | — | — |
| 4BLJ | Galectin-3c in complex with Bisamido-thiogalactoside derivate 2 | x-ray diffraction | A | — | — |
| 4BLJ | Galectin-3C in complex with bisamido-thiogalactoside derivate 2 | x-ray diffraction | A | — | — |
| 4BM8 | Galectin-3c in complex with Bisamido-thiogalactoside derivate 3 | x-ray diffraction | A | — | — |
| 4BM8 | Galectin-3C in complex with bisamido-thiogalactoside derivate 3 | x-ray diffraction | A | — | — |
| 4JC1 | Galectin-3 carbohydrate recognition domain in complex with thiodigalactoside | x-ray diffraction | A | — | — |
| 4JC1 | Galectin-3 carbohydrate recognition domain in complex with thiodigalactoside | x-ray diffraction | A | — | — |
| 4JCK | Galectin-3 carbohydrate recognition domain in complex with thioditaloside | x-ray diffraction | A | — | — |
| 4JCK | Galectin-3 carbohydrate recognition domain in complex with thioditaloside | x-ray diffraction | A | — | — |
| 4LBJ | Crystal structure of Human galectin-3 CRD K176L mutant in complex with LNT | x-ray diffraction | A | — | — |
| 4LBJ | Crystal structure of human galectin-3 crd K176L mutant in complex with lnt | x-ray diffraction | A | — | — |
| 4LBK | Crystal structure of Human galectin-3 CRD K176L mutant in complex with LNnT | x-ray diffraction | A | — | — |
| 4LBK | Crystal structure of human galectin-3 crd K176L mutant in complex with lnnt | x-ray diffraction | A | — | — |
| 4LBL | Crystal structure of Human galectin-3 CRD K176L mutant in complex with a-GM3 | x-ray diffraction | A | — | — |
| 4LBL | Crystal structure of human galectin-3 crd K176L mutant in complex with a-GM3 | x-ray diffraction | A | — | — |
| 4LBM | Crystal structure of Human galectin-3 CRD in complex with LNT | x-ray diffraction | A | — | — |
| 4LBM | Crystal structure of human galectin-3 crd in complex with lnt | x-ray diffraction | A | — | — |
| 4LBN | Crystal structure of Human galectin-3 CRD in complex with LNnT | x-ray diffraction | A | — | — |
| 4LBN | Crystal structure of human galectin-3 crd in complex with lnnt | x-ray diffraction | A | — | — |
| 4LBO | Crystal structure of Human galectin-3 CRD in complex with a-GM3 | x-ray diffraction | A | — | — |
| 4LBO | Crystal structure of human galectin-3 crd in complex with a-GM3 | x-ray diffraction | A | — | — |
| 4R9A | Crystal structure of Human galectin-3 CRD in complex with lactose (pH 7.0, PEG4000) | x-ray diffraction | A | — | — |
| 4R9A | Crystal structure of human galectin-3 crd in complex with lactose (pH 7.0, PEG4000) | x-ray diffraction | A | — | — |
| 4R9B | Crystal structure of Human galectin-3 CRD in complex with lactose (pH 7.0, PEG 6000) | x-ray diffraction | A | — | — |
| 4R9B | Crystal structure of human galectin-3 crd in complex with lactose (pH 7.0, peg 6000) | x-ray diffraction | A | — | — |
127 records more on the page itself.
Ligands
- CL · Chloride ion · in 48 records
- GAL · beta-D-galactopyranose · in 14 records
- SCN · Thiocyanate ion · in 10 records
- BGC · beta-D-glucopyranose · in 6 records
- YIO · 1-thio-beta-D-galactopyranose · in 5 records
- J0T · (2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-2-[(2~{R})-3-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-2-oxidanyl-propyl]sulfanyl-6-(hydroxymethyl)oxane-3,5-diol · in 4 records
- MG · Magnesium ion · in 4 records
- TVD · N-acetyl-2-(acetylamino)-2-deoxy-beta-D-glucopyranosylamine · in 4 records
- 5A4 · methyl 2-O-(4-fluoro-2-nitrobenzoyl)-3-O-(4-methylbenzoyl)-beta-D-talopyranoside · in 3 records
- ADA · alpha-D-galactopyranuronic acid · in 3 records
- GTR · beta-D-galactopyranuronic acid · in 3 records
- J1E · (2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-2-[(2~{S})-3-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-2-oxidanyl-propyl]sulfanyl-6-(hydroxymethyl)oxane-3,5-diol · in 3 records
- SO4 · Sulfate ion · in 3 records
- 4IW · (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2S,3R,4S,5R, 6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]diselanyl}oxane-3,4,5-triol (non-preferred name) · in 2 records
- 4IZ · beta-D-galactopyranosyl 1-seleno-beta-D-galactopyranoside · in 2 records
- 57I · methyl 3-O-(4-methylbenzoyl)-2-O-(2-nitrobenzoyl)-beta-D-talopyranoside · in 2 records
- 59O · Methyl 2-O-(4-chloro-2-nitrobenzoyl)-3-O-(4-methylbenzoyl)-beta-D-talopyranoside · in 2 records
- 5BI · methyl 3-O-(4-methylbenzoyl)-2-O-[2-nitro-4-(trifluoromethyl)benzoyl]-beta-D-talopyranoside · in 2 records
- 5EI · methyl 3-O-(4-methylbenzoyl)-2-O-(3-nitrobenzoyl)-beta-D-talopyranoside · in 2 records
- 8VW · ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-2-acetamido-6-(hydroxymethyl)-5-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4-oxidanyl-oxan-3-yl]-3-methoxy-benzamide · in 2 records
- 9SK · 5,6-bis(fluoranyl)-3-[[(2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,5-bis(oxidanyl)-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxan-2-yl]sulfanyl-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]chromen-2-one · in 2 records
- BKH · (2~{R},3~{R},4~{S},5~{R},6~{R})-2-(3,4-dichlorophenyl) sulfanyl-6-(hydroxymethyl)-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol · in 2 records
- EGZ · (3~{R},5~{R},6~{S},7~{S},8~{R},13~{S})-5-(hydroxymethyl)-7-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-6-oxidanyl-11-oxidanylidene-2,4-dioxa-9-thia-12-azatricyclo[8.4.0.0^{3,8}]tetradec-1(10)-ene-13-carboxylic acid · in 2 records
- H5H · (2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-4-[4-[2,3,5,6-tetrakis(fluoranyl)-4-(methylamino)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol · in 2 records
- H5Q · (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-[4-azanyl-2,3,5,6-tetrakis(fluoranyl)phenyl]-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol · in 2 records
- H5T · (2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-4-[4-[2,3,5,6-tetrakis(fluoranyl)-4-oxidanyl-phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol · in 2 records
- H5Z · (2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-4-[4-[2,3,4,5,6-pentakis(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3, 5-diol · in 2 records
- J4N · (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-[3,5-bis(fluoranyl)phenyl]-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol · in 2 records
- J5Q · (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol · in 2 records
- J62 · (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-(4-fluoranyl-3-methyl-phenyl)-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol · in 2 records
Elsewhere
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