UniProt P16330
2',3'-cyclic-nucleotide 3'-phosphodiesterase (P16330)
2',3'-cyclic-nucleotide 3'-phosphodiesterase (UniProt P16330), EC 3.1.4.37: 66 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 26 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P16330
- Protein
- 2',3'-cyclic-nucleotide 3'-phosphodiesterase
- EC
- 3.1.4.37
- Experimental structures
- 66
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 26 · 4 records with a druggable one
Structures
67 records of P16330 in the MolNFT archive: 66 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XMI | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, complexed with citrate | x-ray diffraction | A | — | — |
| 2XMI | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, complexed with citrate | x-ray diffraction | A | — | — |
| 2Y1P | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, complexed with citrate | x-ray diffraction | A | — | — |
| 2Y1P | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, complexed with citrate | x-ray diffraction | A | — | — |
| 2Y3X | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, complexed with sulfate | x-ray diffraction | A, B, E | — | — |
| 2Y3X | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, complexed with sulfate | x-ray diffraction | A, B, E | — | — |
| 2YDB | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, soaked with 2',3'-cyclic… | x-ray diffraction | A | — | — |
| 2YDB | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, soaked with 2',3'-cyclic… | x-ray diffraction | A | — | — |
| 2YDC | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, soaked with GTP | x-ray diffraction | A | — | — |
| 2YDC | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, soaked with GTP | x-ray diffraction | A | — | — |
| 2YDD | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, soaked with 2',3'-cyclic… | x-ray diffraction | A | — | — |
| 2YDD | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, soaked with 2',3'-cyclic… | x-ray diffraction | A | — | — |
| 2YOZ | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, crystallized with 2'-AMPS | x-ray diffraction | A | — | — |
| 2YOZ | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, crystallized with 2'-amps | x-ray diffraction | A | — | — |
| 2YP0 | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, crystallized with 2'-AMPS | x-ray diffraction | A | — | — |
| 2YP0 | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, crystallized with 2'-amps | x-ray diffraction | A | — | — |
| 2YPC | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S… | x-ray diffraction | A | — | — |
| 2YPC | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S… | x-ray diffraction | A | — | — |
| 2YPE | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S… | x-ray diffraction | A | — | — |
| 2YPE | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S… | x-ray diffraction | A | — | — |
| 2YPH | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S… | x-ray diffraction | A | — | — |
| 2YPH | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S… | x-ray diffraction | A | — | — |
| 2YQ9 | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A… | x-ray diffraction | A | — | — |
| 2YQ9 | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A… | x-ray diffraction | A | — | — |
| 3ZBR | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S… | x-ray diffraction | A, B | — | — |
| 3ZBR | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S… | x-ray diffraction | A, B | — | — |
| 3ZBS | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A… | x-ray diffraction | A | — | — |
| 3ZBS | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A… | x-ray diffraction | A | — | — |
| 3ZBZ | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A… | x-ray diffraction | A | — | — |
| 3ZBZ | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A… | x-ray diffraction | A | — | — |
| 4WBI | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutations H230Q and… | x-ray diffraction | A | — | — |
| 4WBI | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutations H230Q and… | x-ray diffraction | A | — | — |
| 4WBL | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation F235A | x-ray diffraction | A | — | — |
| 4WBL | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation F235A | x-ray diffraction | A | — | — |
| 4WC9 | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation F235L | x-ray diffraction | A | — | — |
| 4WC9 | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation F235L | x-ray diffraction | A | — | — |
| 4WCA | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230Q… | x-ray diffraction | A | — | — |
| 4WCA | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230Q… | x-ray diffraction | A | — | — |
| 4WCB | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309Q | x-ray diffraction | A | — | — |
| 4WCB | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309Q | x-ray diffraction | A | — | — |
| 4WCC | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation P225G | x-ray diffraction | A | — | — |
| 4WCC | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation P225G | x-ray diffraction | A | — | — |
| 4WDA | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation P296G… | x-ray diffraction | A | — | — |
| 4WDA | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation P296G… | x-ray diffraction | A | — | — |
| 4WDB | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation R307Q… | x-ray diffraction | A | — | — |
| 4WDB | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation R307Q… | x-ray diffraction | A | — | — |
| 4WDD | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation T232A… | x-ray diffraction | A | — | — |
| 4WDD | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation T232A… | x-ray diffraction | A | — | — |
| 4WDE | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation T311A | x-ray diffraction | A, B | — | — |
| 4WDE | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation T311A | x-ray diffraction | A, B | — | — |
| 4WDF | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A… | x-ray diffraction | A | — | — |
| 4WDF | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A… | x-ray diffraction | A | — | — |
| 4WDG | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A… | x-ray diffraction | A | — | — |
| 4WDG | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A… | x-ray diffraction | A | — | — |
| 4WDH | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation Y168A | x-ray diffraction | A | — | — |
| 4WDH | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation Y168A | x-ray diffraction | A | — | — |
| 4WEX | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation Y168S | x-ray diffraction | A | — | — |
| 4WEX | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation Y168S | x-ray diffraction | A | — | — |
| 4WFR | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation T232A… | x-ray diffraction | A | — | — |
| 4WFR | Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation T232A… | x-ray diffraction | A | — | — |
7 records more on the page itself.
Ligands
Experiment against prediction
- 9ETL chain B against the predicted model P16330: TM-score 0.98, RMSD 0.86 Å
- 9ETL chain A against the predicted model P16330: TM-score 0.98, RMSD 0.87 Å
- 4WCA chain A against the predicted model P16330: TM-score 0.98, RMSD 0.86 Å
- 4WCA chain A against the predicted model P16330: TM-score 0.98, RMSD 0.86 Å
- 2YDD chain A against the predicted model P16330: TM-score 0.97, RMSD 0.97 Å
- 2YDD chain A against the predicted model P16330: TM-score 0.97, RMSD 0.97 Å
- 4WFR chain A against the predicted model P16330: TM-score 0.97, RMSD 0.97 Å
- 4WFR chain A against the predicted model P16330: TM-score 0.97, RMSD 0.97 Å
- 4WCC chain A against the predicted model P16330: TM-score 0.97, RMSD 0.97 Å
- 4WCC chain A against the predicted model P16330: TM-score 0.97, RMSD 0.97 Å
Elsewhere
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