UniProt P16083
Ribosyldihydronicotinamide dehydrogenase [quinone] (P16083)
Ribosyldihydronicotinamide dehydrogenase [quinone] (UniProt P16083), EC 1.10.5.1, 1.10.99.2: 133 experimental structures on GenesisL1, 10 ligands bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P16083
- Protein
- Ribosyldihydronicotinamide dehydrogenase [quinone]
- EC
- 1.10.5.1, 1.10.99.2
- Experimental structures
- 133
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 6 · 3 records with a druggable one
Structures
133 records of P16083 in the MolNFT archive: 133 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1QR2 | Human quinone reductase type 2 | x-ray diffraction | A, B | — | — |
| 1QR2 | Human quinone reductase type 2 | x-ray diffraction | A, B | — | — |
| 1SG0 | Crystal structure analysis of QR2 in complex with resveratrol | x-ray diffraction | A, B | — | — |
| 1SG0 | Crystal structure analysis of QR2 in complex with resveratrol | x-ray diffraction | A, B | — | — |
| 1XI2 | Qui Reductase 2 in Complex with Cancer Prodrug CB1954 | x-ray diffraction | A, B | — | — |
| 1XI2 | Quinone reductase 2 in complex with cancer prodrug CB1954 | x-ray diffraction | A, B | — | — |
| 1ZX1 | Human qui oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954 | x-ray diffraction | A, B | — | — |
| 1ZX1 | Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954 | x-ray diffraction | A, B | — | — |
| 2BZS | Binding of anti-cancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal… | x-ray diffraction | A, B | — | — |
| 2BZS | Binding of anti-cancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal… | x-ray diffraction | A, B | — | — |
| 2QMY | Qui Reductase 2 in complex with adrenochrome | x-ray diffraction | A, B | — | — |
| 2QMY | Quinone reductase 2 in complex with adrenochrome | x-ray diffraction | A, B | — | — |
| 2QMZ | Qui Reductase 2 in Complex with Dopamine | x-ray diffraction | A, B | — | — |
| 2QMZ | Quinone reductase 2 in complex with dopamine | x-ray diffraction | A, B | — | — |
| 2QR2 | Human quinone reductase type 2, complex with menadione | x-ray diffraction | A, B | — | — |
| 2QR2 | Human quinone reductase type 2, complex with menadione | x-ray diffraction | A, B | — | — |
| 2QWX | Crystal Structure of Qui Reductase II | x-ray diffraction | A, B | — | — |
| 2QWX | Crystal structure of quinone reductase II | x-ray diffraction | A, B | — | — |
| 2QX4 | Crystal Structure of Qui Reductase II | x-ray diffraction | A, B | — | — |
| 2QX4 | Crystal structure of quinone reductase II | x-ray diffraction | A, B | — | — |
| 2QX6 | Crystal Structure of Qui Reductase II | x-ray diffraction | A, B | — | — |
| 2QX6 | Crystal structure of quinone reductase II | x-ray diffraction | A, B | — | — |
| 2QX8 | Crystal Structure of Qui Reductase II | x-ray diffraction | A, B | — | — |
| 2QX8 | Crystal structure of quinone reductase II | x-ray diffraction | A, B | — | — |
| 2QX9 | Crystal Structure of Qui Reductase II | x-ray diffraction | A, B | — | — |
| 2QX9 | Crystal structure of quinone reductase II | x-ray diffraction | A, B | — | — |
| 3FW1 | Qui Reductase 2 | x-ray diffraction | A | — | — |
| 3FW1 | Quinone reductase 2 | x-ray diffraction | A | — | — |
| 3G5M | Synthesis of Casimiroin and Optimization of Its Qui Reductase 2 and Aromatase Inhibitory activity | x-ray diffraction | A, B | — | — |
| 3G5M | Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory… | x-ray diffraction | A, B | — | — |
| 3GAM | Synthesis of Casimiroin and Optimization of Its Qui Reductase 2 and Aromatase Inhibitory activity | x-ray diffraction | A, B | — | — |
| 3GAM | Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory… | x-ray diffraction | A, B | — | — |
| 3NFR | Casimiroin analog inhibitor of qui reductase 2 | x-ray diffraction | A, B | — | — |
| 3NFR | Casimiroin analog inhibitor of quinone reductase 2 | x-ray diffraction | A, B | — | — |
| 3NHF | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3NHF | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3NHJ | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3NHJ | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3NHK | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3NHK | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3NHL | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3NHL | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3NHP | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3NHP | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3NHR | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3NHR | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3NHS | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3NHS | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3NHU | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3NHU | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3NHW | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3NHW | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3NHY | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3NHY | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3O2N | X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to… | x-ray diffraction | A, B | — | — |
| 3O2N | X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to… | x-ray diffraction | A, B | — | — |
| 3O73 | Crystal structure of qui reductase 2 in complex with the indolequi MAC627 | x-ray diffraction | A, B | — | — |
| 3O73 | Crystal structure of quinone reductase 2 in complex with the indolequinone MAC627 | x-ray diffraction | A, B | — | — |
| 3OVM | X-ray Structural study of qui reductase II inhibition by compounds with micromolar to nanomolar… | x-ray diffraction | A, B | — | — |
| 3OVM | X-ray structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar… | x-ray diffraction | A, B | — | — |
73 records more on the page itself.
Ligands
- FAD · Flavin-adenine dinucleotide · in 10 records
- ZN · Zinc ion · in 10 records
- SO4 · Sulfate ion · in 7 records
- 6T0 · 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine · in 2 records
- C09 · 2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine · in 2 records
- V0L · volitinib · in 2 records
- 6T2 · 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine · in 1 record
- 6T3 · 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene · in 1 record
- ET · Ethidium · in 1 record
- V1Z · 8-methyl-2-(4-methyl-3-piperazin-1-ylsulfonyl-phenyl) imidazo[1,2-a]pyridine · in 1 record
Elsewhere
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