UniProt P15442
P15442
P15442 (UniProt P15442): 14 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P15442
- Experimental structures
- 14
- Predicted models
- 1
Structures
15 records of P15442 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZXE | Crystal Structure of eIF2alpha Protein Kinase GCN2: D835N Inactivating Mutant in Apo Form | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1ZXE | Crystal structure of EIF2ALPHA protein kinase GCN2: D835N inactivating mutant in apo form | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1ZY4 | Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant in Apo Form. | x-ray diffraction | A, B | — | — |
| 1ZY4 | Crystal structure of EIF2ALPHA protein kinase GCN2: R794G hyperactivating mutant in apo form. | x-ray diffraction | A, B | — | — |
| 1ZY5 | Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant Complexed with… | x-ray diffraction | A, B | — | — |
| 1ZY5 | Crystal structure of EIF2ALPHA protein kinase GCN2: R794G hyperactivating mutant complexed with… | x-ray diffraction | A, B | — | — |
| 1ZYC | Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type in Apo Form. | x-ray diffraction | A, B, C, D | — | — |
| 1ZYC | Crystal structure of EIF2ALPHA protein kinase GCN2: wild-type in apo form. | x-ray diffraction | A, B, C, D | — | — |
| 1ZYD | Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type Complexed with ATP. | x-ray diffraction | A, B | — | — |
| 1ZYD | Crystal structure of EIF2ALPHA protein kinase GCN2: wild-type complexed with ATP. | x-ray diffraction | A, B | — | — |
| 2YZ0 | Solution Structure of RWD/GI domain of Saccharomyces cerevisiae GCN2 | solution nmr | A | — | — |
| 2YZ0 | Solution structure of RWD/GI domain of saccharomyces cerevisiae GCN2 | solution nmr | A | — | — |
| 4OTM | Crystal structure of the C-terminal domain from yeast GCN2 | x-ray diffraction | A, B | — | — |
| 4OTM | Crystal structure of the C-terminal domain from yeast GCN2 | x-ray diffraction | A, B | — | — |
| P15442 | AlphaFold monomer V2.0 prediction for eif-2-alpha kinase GCN2 (P15442) | predicted | A | — | — |
Experiment against prediction
- 1ZXE chain F against the predicted model P15442: TM-score 0.98, RMSD 0.90 Å
- 1ZXE chain F against the predicted model P15442: TM-score 0.98, RMSD 0.90 Å
- 1ZXE chain B against the predicted model P15442: TM-score 0.97, RMSD 1.10 Å
- 1ZXE chain B against the predicted model P15442: TM-score 0.97, RMSD 1.10 Å
- 1ZYD chain B against the predicted model P15442: TM-score 0.97, RMSD 1.12 Å
- 1ZYD chain B against the predicted model P15442: TM-score 0.97, RMSD 1.12 Å
- 1ZYC chain D against the predicted model P15442: TM-score 0.97, RMSD 1.11 Å
- 1ZYC chain D against the predicted model P15442: TM-score 0.97, RMSD 1.11 Å
- 1ZXE chain D against the predicted model P15442: TM-score 0.97, RMSD 1.32 Å
- 1ZXE chain D against the predicted model P15442: TM-score 0.97, RMSD 1.32 Å
Elsewhere
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