UniProt P13807
Glycogen [starch] synthase, muscle (P13807)
Glycogen [starch] synthase, muscle (UniProt P13807), EC 2.4.1.11: 11 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 38 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P13807
- Protein
- Glycogen [starch] synthase, muscle
- EC
- 2.4.1.11
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 38 · 2 records with a druggable one
Structures
12 records of P13807 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7Q0B | Human GYS1-GYG1 complex inhibited state | electron microscopy | A, B, C, D | — | — |
| 7Q0S | Human GYS1-GYG1 complex inhibited-like state bound to glucose-6-phosphate | electron microscopy | A, B, C, D | G6P | — |
| 7Q0S | Human GYS1-GYG1 complex inhibited-like state bound to glucose-6- phosphate | electron microscopy | A, B, C, D | G6P | — |
| 7Q12 | Human GYS1-GYG1 complex activated state bound to glucose-6-phosphate | electron microscopy | A, B, C, D | G6P | — |
| 7Q13 | Human GYS1-GYG1 complex activated state bound to glucose-6-phosphate, uridine diphosphate, and… | electron microscopy | A, B, C, D | G6P, UDP, GLC | — |
| 7ZBN | Cryo-EM structure of the human gs-gn complex in the inhibited state | electron microscopy | A, B, C, D | — | — |
| 8CVX | Human glycogenin-1 and glycogen synthase-1 complex in the presence of glucose-6-phosphate | electron microscopy | A, B, D, C | G6P | 20 (best 0.65) |
| 8CVX | Human glycogenin-1 and glycogen synthase-1 complex in the presence of glucose-6-phosphate | electron microscopy | A, B, D, C | G6P | — |
| 8CVY | Human glycogenin-1 and glycogen synthase-1 complex in the apo mobile state | electron microscopy | A, C, D, B | — | — |
| 8CVZ | Human glycogenin-1 and glycogen synthase-1 complex in the apo ordered state | electron microscopy | B, C, D, A | — | 18 (best 0.79) |
| 8CVZ | Human glycogenin-1 and glycogen synthase-1 complex in the apo ordered state | electron microscopy | B, C, D, A | — | — |
| P13807 | AlphaFold monomer V2.0 prediction for glycogen [starch] synthase, muscle (P13807) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8CVZ chain A against the predicted model P13807: TM-score 0.99, RMSD 0.98 Å
- 8CVZ chain A against the predicted model P13807: TM-score 0.99, RMSD 0.98 Å
- 8CVZ chain B against the predicted model P13807: TM-score 0.99, RMSD 1.08 Å
- 8CVZ chain B against the predicted model P13807: TM-score 0.99, RMSD 1.08 Å
- 8CVY chain A against the predicted model P13807: TM-score 0.99, RMSD 1.07 Å
- 8CVY chain B against the predicted model P13807: TM-score 0.99, RMSD 0.80 Å
- 8CVY chain D against the predicted model P13807: TM-score 0.98, RMSD 1.11 Å
- 8CVY chain C against the predicted model P13807: TM-score 0.98, RMSD 1.15 Å
- 8CVZ chain C against the predicted model P13807: TM-score 0.98, RMSD 1.20 Å
- 8CVZ chain C against the predicted model P13807: TM-score 0.98, RMSD 1.20 Å
Elsewhere
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