UniProt P13498
Cytochrome b-245 light chain (P13498)
Cytochrome b-245 light chain (UniProt P13498): 9 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P13498
- Protein
- Cytochrome b-245 light chain
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 16 · 6 records with a druggable one
Structures
10 records of P13498 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WLP | Solution Structure Of The P22Phox-P47Phox Complex | solution nmr | A | — | 1 (best 0.42) |
| 1WLP | Solution structure of the P22PHOX-P47PHOX complex | solution nmr | A | — | 1 (best 0.42) |
| 7U8G | Cryo-EM structure of the core human NADPH oxidase NOX2 | electron microscopy | B | POV | 1 (best 0.85) |
| 7YXW | Structure of the p22phox A200G mutant in complex with p47phox peptide | x-ray diffraction | D | — | 1 (best 0.47) |
| 7YXW | Structure of the P22PHOX A200G mutant in complex with P47PHOX peptide | x-ray diffraction | D | — | 1 (best 0.47) |
| 8GZ3 | Structure of human phagocyte NADPH oxidase in the resting state | electron microscopy | A | HEM, LBN | 2 (best 0.82) |
| 8KEI | Cryo-EM structure of NADPH oxidase 2 in complex with p22phox and EROS | electron microscopy | A | POV, LBN | 3 (best 0.81) |
| 8WEJ | Structure of human phagocyte NADPH oxidase in the activated state | electron microscopy | A | HEM | 2 (best 0.82) |
| 8X2L | Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH | electron microscopy | A | HEM | 3 (best 0.82) |
| P13498 | AlphaFold monomer V2.0 prediction for cytochrome B-245 light chain (P13498) | predicted | A | — | 1 (best 0.56) |
Ligands
Experiment against prediction
- 7U8G chain B against the predicted model P13498: TM-score 0.99, RMSD 0.52 Å
- 8GZ3 chain A against the predicted model P13498: TM-score 0.99, RMSD 0.53 Å
- 8X2L chain A against the predicted model P13498: TM-score 0.98, RMSD 0.54 Å
- 8WEJ chain A against the predicted model P13498: TM-score 0.98, RMSD 0.62 Å
- 8KEI chain A against the predicted model P13498: TM-score 0.96, RMSD 0.94 Å
- 7YXW chain D against the predicted model P13498: TM-score 0.42, RMSD 1.37 Å
- 7YXW chain D against the predicted model P13498: TM-score 0.42, RMSD 1.37 Å
- 1WLP chain A against the predicted model P13498: TM-score 0.30, RMSD 2.08 Å
- 1WLP chain A against the predicted model P13498: TM-score 0.30, RMSD 2.08 Å
Elsewhere
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