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UniProt P13433

DNA-directed RNA polymerase, mitochondrial (P13433)

DNA-directed RNA polymerase, mitochondrial (UniProt P13433), EC 2.7.7.6: 10 experimental structures on GenesisL1, 3 ligands bound, 127 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P13433
Protein
DNA-directed RNA polymerase, mitochondrial
EC
2.7.7.6
Experimental structures
10
Predicted models
0
Ligands
3
Pockets
127 · 7 records with a druggable one

Structures

10 records of P13433 in the MolNFT archive: 10 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6YMVCryo-EM structure of yeast mitochondrial RNA polymerase partially-melted transcription initiation…electron microscopyA—17 (best 0.81)
6YMVCryo-EM structure of yeast mitochondrial RNA polymerase partially- melted transcription initiation…electron microscopyA——
6YMWCryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complexelectron microscopyAP5E, MG17 (best 0.84)
6YMWCryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complexelectron microscopyAP5E, MG—
8ATTCryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 4-mer…electron microscopyAGTP17 (best 0.84)
8ATWCryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 6-mer…electron microscopyAGTP19 (best 0.82)
8C5SCryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 7-mer…electron microscopyA—19 (best 0.84)
8C5UCryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 8-mer…electron microscopyA—19 (best 0.79)
8Q63Cryo-EM structure of IC8', a second state of yeast mitochondrial RNA polymerase transcription…electron microscopyA—19 (best 0.78)
P13433AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase, mitochondrial (P13433)———

Ligands

  • GTP · Guanosine-5'-triphosphate · in 2 records
  • MG · Magnesium ion · in 2 records
  • P5E · [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene) pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl] phosphono hydrogen phosphate · in 2 records

Elsewhere

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