UniProt P12969
amylin peptide (P12969)
amylin peptide (UniProt P12969): 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P12969
- Protein
- amylin peptide
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 4 · 2 records with a druggable one
Structures
11 records of P12969 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2KJ7 | Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles | solution nmr | A | — | — |
| 2KJ7 | Three-dimensional NMR structure of rat islet amyloid polypeptide in dpc micelles | solution nmr | A | — | — |
| 7TYF | Human Amylin1 Receptor in complex with Gs and rat amylin peptide | electron microscopy | P | P42 | — |
| 7TYF | Human AMYLIN1 receptor in complex with gs and rat amylin peptide | electron microscopy | P | NH2, P42 | — |
| 7TYI | Calcitonin receptor in complex with gs and rat amylin peptide, ct-like state | electron microscopy | P | NH2, PLM | — |
| 7TYL | Calcitonin Receptor in complex with Gs and rat amylin peptide, bypass motif | electron microscopy | P | — | 2 (best 0.75) |
| 7TYL | Calcitonin receptor in complex with gs and rat amylin peptide, bypass motif | electron microscopy | P | NH2 | — |
| 7TYX | Human Amylin2 Receptor in complex with Gs and rat amylin peptide | electron microscopy | P | PLM | 2 (best 0.74) |
| 7TYX | Human AMYLIN2 receptor in complex with gs and rat amylin peptide | electron microscopy | P | NH2, PLM | — |
| 7TZF | Human AMYLIN3 receptor in complex with gs and rat amylin peptide | electron microscopy | P | NH2, P42 | — |
| P12969 | AlphaFold monomer V2.0 prediction for islet amyloid polypeptide (P12969) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2KJ7 chain A against the predicted model P12969: TM-score 0.44, RMSD 2.47 Å
- 2KJ7 chain A against the predicted model P12969: TM-score 0.44, RMSD 2.47 Å
- 7TYI chain P against the predicted model P12969: TM-score 0.37, RMSD 3.28 Å
- 7TYL chain P against the predicted model P12969: TM-score 0.37, RMSD 2.95 Å
- 7TYL chain P against the predicted model P12969: TM-score 0.37, RMSD 2.95 Å
- 7TZF chain P against the predicted model P12969: TM-score 0.36, RMSD 2.86 Å
- 7TYX chain P against the predicted model P12969: TM-score 0.36, RMSD 2.87 Å
- 7TYX chain P against the predicted model P12969: TM-score 0.36, RMSD 2.87 Å
- 7TYF chain P against the predicted model P12969: TM-score 0.36, RMSD 2.06 Å
- 7TYF chain P against the predicted model P12969: TM-score 0.36, RMSD 2.06 Å
Elsewhere
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